Serum Amyloid A1 Products

Antibodies
Serum Amyloid A1 Antibody (37 ...
Serum Amyloid A1 Antibody (370820)
MAB3019
Species: Hu
Applications: WB
Host: Rat Monoclonal
Serum Amyloid A1 Antibody (90 ...
Serum Amyloid A1 Antibody (902738)
MAB30191
Species: Hu
Applications: IHC
Host: Mouse Monoclonal
Serum Amyloid A1 Antibody (mc ...
Serum Amyloid A1 Antibody (mc1)
NB100-65715
Species: Hu
Applications: IHC, IHC-Fr, IHC-P
Host: Mouse Monoclonal
Lysates
Serum Amyloid A1 Overexpressi ...
Serum Amyloid A1 Overexpression Ly...
NBL1-15671
Applications: WB
Serum Amyloid A1 Overexpressi ...
Serum Amyloid A1 Overexpression Ly...
NBL1-15670
Applications: WB
Serum Amyloid A1 Overexpressi ...
Serum Amyloid A1 Overexpression Ly...
H00006288-T02
Species: Hu
Applications: WB
Proteins
Recombinant Human Serum Amylo ...
Recombinant Human Serum Amyloid A1...
NBP1-30209
Species: Hu
Applications: PAGE
Recombinant Human Serum Amylo ...
Recombinant Human Serum Amyloid A1...
NBP2-34875
Species: Hu
Applications: Func, PAGE
Recombinant Primate Serum Amy ...
Recombinant Primate Serum Amyloid ...
NBP2-35320
Species: Pm
Applications: Func, PAGE
RNAi
Serum Amyloid A1 RNAi
Serum Amyloid A1 RNAi
H00006288-R02
Species: Hu
Applications: RNAi, RNAi SP
Serum Amyloid A1 RNAi
Serum Amyloid A1 RNAi
H00006288-R01
Species: Hu
Applications: RNAi, RNAi SP

Description

The serum amyloid A (SAA) family comprises a number of differentially expressed lipoproteins, acute phase SAA1 and SAA2, the former being a major component in plasma, and constitutive SAA's (C-SAAs). Although the liver is the primary site of synthesis of both SAA types, extrhepatic production has been reported. The in vivo concentrations increase by as much as 1000 fold during inflammation. Several studies have expressed its importance in the diagnosis and monitoring of various diseases. Pathological SAA values are often detected in association with normal CRP concentrations. SAA rises earlier and more sharply than CRP. SAA enhances the binding of HDL's to macrophages and thus helps the delivery of lipid to sites of injury for use in tissue repair. It is thus thought to be an integral part of the disease process. In addition, recent experiments suggest that SAA may play a quot houekeeping quot role in normal human tissues. Elevated levels of SAA over time predispose secondary amyloidosis, extracellular accumulation of amyloid fibrils, derived from a circulating precursor, in various tissues and organs. The most common form of amyloidosis occurs secondary to chronic inflammatory disease, particularly rheumatoid artheritis. Amyloidosis is a heterogeneous group of disorders characterized by extracellular deposition of abnormal protein fibrils, which are derived from different proteins. Almost all patients with amyloidosis have some level of renal disorders. The immunoperoxidase technique has the advantage of being able to detect amyloid in formalin-fixed paraffin embedded tissues and is a very specific method for identifying amyloid fibril proteins. Small and minute amounts of amyloid can be detected with both Amyloid P (ab688) and Amyloid A antibodies, and thus could allow earlier treatment before organ damage has occurred.

Bioinformatics

Entrez Human
Monkey
Uniprot Human
Human
Human
Human
Product By Gene ID 6288
Alternate Names
  • tumor protein p53 inducible protein 4
  • SAA
  • serum amyloid A protein
  • TP53I4
  • SAA2
  • PIG4
  • MGC111216
  • serum amyloid A1

Research Areas for Serum Amyloid A1

Find related products by research area and learn more about each of the different research areas below.

Alzheimers Research
Cancer
Neuroscience

PTMs for Serum Amyloid A1

Learn more about PTMs related to Serum Amyloid A1.

Cleavage
Nitration
Phosphorylation
Methylation
Glycosylation

Bioinformatics Tool for Serum Amyloid A1

Discover related pathways, diseases and genes to Serum Amyloid A1. Need help? Read the Bioinformatics Tool Guide for instructions on using this tool.
 
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