Serpin E1/PAI-1 Antibody (I-1) - BSA Free

Product Discontinued

Serpin E1/PAI-1 Antibody (I-1) - BSA Free Summary

• Immunogen: Partially purified human PAI-1
• Epitope: Differs from that of Clone I-2, Clone I-3 and Clone I-5.
• Specificity: Clone I-1 is specific for human PAI-1. No cross-reactivity is observed with PAI-2 as tested by ELISA and immunoblotting. No reactivity is observed with any other human plasma protein when tested by immunoblotting.
• Isotype: IgG1
• Clonality: Monoclonal
• Host: Mouse
• Gene: SERPINE1
• Purity: Protein A or G purified

Applications/Dilutions

• Dilutions:
  • ELISA 1:100-1:2000
  • Immunoaffinity Purification
  • Immunohistochemistry 1:10-1:500
  • Western Blot 1:100-1:2000
• Application Notes: ELISA: NBP2-23509 reacts with PAI-1 as tested by ELISA. (1) WB: NBP2-23509 reacts with PAI-1 as tested by immunoblotting. IHC: NBP2-23509 can be used in IHC. AP: NBP2-23509 reacts with PAI-1 as tested by affinity purificaton.

Packaging, Storage & Formulations

• Storage: Store at 4C in the dark.
• Buffer: 10mM Phosphate (pH 7.4) and 0.14M NaCl
• Preservative: 0.09% Sodium Azide
• Concentration: 1 mg/ml
• Purity: Protein A or G purified

Alternate Names for Serpin E1/PAI-1 Antibody (I-1) - BSA Free

• Endothelial plasminogen activator inhibitor
• Nexin
• PAI1
• PAI-1
• PAI1PAI-1
• PAISerpin E1
• PLANH1
• PLANH1plasminogen activator inhibitor 1
• serine (or cysteine) proteinase inhibitor, clade E (nexin, plasminogenactivator inhibitor type 1), member 1
• Serpin E1
• serpin peptidase inhibitor, clade E (nexin, plasminogen activator inhibitortype 1), member 1

Background

Plasminogen activator inhibitor-1 (PAI-1) is the principal inhibitor of urokinase plasminogen activator (uPA) and tissue plasminogen activator (tPA). It belongs to the group of serpins (serine protease inhibitors). Elevated tumor and/or plasma levels of PAI-1 are associated with poor prognosis in many types of cancer.

Limitations

This product is for research use only and is not approved for use in humans or in clinical diagnosis. Primary Antibodies are guaranteed for 1 year from date of receipt.

Bioinformatics

• Gene Symbol: SERPINE1