Serpin E1/PAI-1 Antibody (367612) [Alexa Fluor® 488]

• Reactivity: Mu
• Applications: WB
• Clone: 367612
• Clonality: Monoclonal
• Host: Rat
• Conjugate: Alexa Fluor 488

Serpin E1/PAI-1 Antibody (367612) [Alexa Fluor® 488] Summary

• Immunogen: Mouse myeloma cell line NS0-derived recombinant mouse Serpin E1/PAI‑1
  Leu24-Ser402
  Accession # AAH54091
• Specificity: Detects mouse Serpin E1/PAI‑1 in direct ELISAs and Western blots. In Western blots, no cross-reactivity with recombinant mouse Serpin A1, A5, A6, B8, C1, D1, E2, F1, F2, I1, recombinant human Serpin A3, A4, B6, B9, G1, or I2 is observed.
• Isotype: IgG2a
• Clonality: Monoclonal
• Host: Rat
• Purity Statement: Protein A or G purified

Applications/Dilutions

• Dilutions:
  • Western Blot

Packaging, Storage & Formulations

• Storage: Protect from light. Do not freeze. 12 months from date of receipt, 2 to 8 °C as supplied
• Buffer: Supplied 0.2mg/ml in 1X PBS with RDF1 and 0.09% Sodium Azide

Notes

This product is produced by and ships from R&D Systems, Inc., a Bio-Techne brand.

Alternate Names for Serpin E1/PAI-1 Antibody (367612) [Alexa Fluor® 488]

• Endothelial plasminogen activator inhibitor
• Nexin
• PAI1
• PAI-1
• PAI1PAI-1
• PAISerpin E1
• PLANH1
• PLANH1plasminogen activator inhibitor 1
• serine (or cysteine) proteinase inhibitor, clade E (nexin, plasminogenactivator inhibitor type 1), member 1
• Serpin E1
• serpin peptidase inhibitor, clade E (nexin, plasminogen activator inhibitortype 1), member 1

Background

Serpin E1, also known as Plasminogen Activator Inhibitor-1 (PAI-1), is the principal inhibitor of urokinase-type and tissue-type plasminogen activators. It plays a major role in many processes such as angiogenesis, tumor invasion, and obesity. The amino acid sequence of mouse PAI-1 is 89%, 79% and 76% identical to that of rat, human/chimpanzee and dog.

Limitations

This product is for research use only and is not approved for use in humans or in clinical diagnosis. Primary Antibodies are guaranteed for 1 year from date of receipt.