Serpin C1/Antithrombin-III Antibody (2 E10) - BSA Free

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Immunohistochemistry-Paraffin: Serpin C1/Antithrombin-III Antibody (2 E10) [NBP1-05149] - Paraffin-embedded human liver tissue.
Immunohistochemistry-Paraffin: Serpin C1/Antithrombin-III Antibody (2 E10) [NBP1-05149] - Paraffin-embedded human cancerous liver tissue.

Product Details

Summary
Reactivity HuSpecies Glossary
Applications ELISA, IHC, IHC-P
Clone
2 E10
Clonality
Monoclonal
Host
Mouse
Conjugate
Unconjugated
Format
BSA Free
Concentration
1.0 mg/ml

Serpin C1/Antithrombin-III Antibody (2 E10) - BSA Free Summary

Immunogen
Antithrombin III isolated from human plasma (1)
Localization
Secreted. Found in Plasma.
Specificity
Antithrombin III (human, native and denatured)
Isotype
IgG1 Kappa
Clonality
Monoclonal
Host
Mouse
Gene
SERPINC1
Purity
Protein A or G purified
Innovator's Reward
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Applications/Dilutions

Dilutions
  • ELISA 1:16000
  • Immunohistochemistry 1:10-1:500
  • Immunohistochemistry-Paraffin 1:10-1:500
Application Notes
This product is useful for ELISA and Immunohistochemistry-Paraffin. This Antibody reacts strongly with AT III both native and denatured forms. A strong reaction is seen in ELISA with both native and denatured AT III directly coated onto the microtiter well and also when used as detection antibody in sandwich ELISA in combination with a polyclonal capture antibody.
Theoretical MW
53 kDa.
Disclaimer note: The observed molecular weight of the protein may vary from the listed predicted molecular weight due to post translational modifications, post translation cleavages, relative charges, and other experimental factors.

Packaging, Storage & Formulations

Storage
Store at 4C in the dark.
Buffer
10mM Phosphate (pH 7.4) and 0.5M NaCl
Preservative
15mM Sodium Azide
Concentration
1.0 mg/ml
Purity
Protein A or G purified

Alternate Names for Serpin C1/Antithrombin-III Antibody (2 E10) - BSA Free

  • Antithrombin-III
  • AT3antithrombin-III
  • ATIII
  • ATIIIantithrombin III
  • MGC22579
  • serine (or cysteine) proteinase inhibitor, clade C (antithrombin), member 1
  • serine-cysteine proteinase inhibitor clade C member 1
  • Serpin C1
  • serpin peptidase inhibitor, clade C (antithrombin), member 1

Background

Antithrombin III (AT III) is a single chain glycoprotein of molecular mass 58 kDa with four glycosylation sites and three intra-molecular disulfide bonds. AT III is normally present in human plasma at a concentration of approx. 12.5 mg/dl. It is the major inhibitor of thrombin. Inactivation of thrombin by AT-III occurs by formation of a covalent bond resulting in an inactive 1:1 stoichiometric complex between the two components.

Limitations

This product is for research use only and is not approved for use in humans or in clinical diagnosis. Primary Antibodies are guaranteed for 1 year from date of receipt.

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Bioinformatics

Gene Symbol SERPINC1
Entrez