Serpin A4/Kallistatin Antibody [CoraFluor™ 1]

• Reactivity: Hu
• Applications: WB, IHC, IP, B/N
• Clonality: Polyclonal
• Host: Goat
• Conjugate: CoraFluor 1

Serpin A4/Kallistatin Antibody [CoraFluor™ 1] Summary

• Description: CoraFluor(TM) 1 is a high performance terbium-based TR-FRET (Time-Resolved Fluorescence Resonance Energy Transfer) or TRF (Time-Resolved Fluorescence) donor for high throughput assay development. CoraFluor(TM) 1 absorbs UV light at approximately 340 nm, and emits at approximately 490 nm, 545 nm, 585 nm and 620 nm. It is compatible with common acceptor dyes that absorb at the emission wavelengths of CoraFluor(TM) 1. CoraFluor(TM) 1 can be used for the development of robust and scalable TR-FRET binding assays such as target engagement, ternary complex, protein-protein interaction and protein quantification assays.
  
  CoraFluor(TM) 1, amine reactive
  
  CoraFluor(TM) 1, thiol reactive
  
  For more information, please see our CoraFluor(TM) TR-FRET technology flyer.
• Immunogen: Mouse myeloma cell line NS0-derived recombinant human Serpin A4/Kallistatin
  Gly20-Pro427 (predicted)
  Accession # AAA59454
• Specificity: Detects human Serpin A4/Kallistatin in direct ELISAs and Western blots. In direct ELISAs, less than 5% cross-reactivity with recombinant human (rh) Serpin A1, rhSerpin A3, rhSerpin A5, rhSerpin C1, recombinant mouse Serpin D1, and rhSerpin F2 is observed.
• Isotype: IgG
• Clonality: Polyclonal
• Host: Goat
• Gene: SERPINA4
• Purity: Antigen Affinity-purified

Applications/Dilutions

• Dilutions:
  • Immunohistochemistry
  • Immunoprecipitation
  • Neutralization
  • Western Blot
• Application Notes: Optimal dilution of this antibody should be experimentally determined.

Packaging, Storage & Formulations

• Storage: Store at 4C in the dark. Do not freeze.
• Buffer: PBS
• Preservative: No Preservative
• Purity: Antigen Affinity-purified

Notes

CoraFluor (TM) is a trademark of Bio-Techne Corp. Sold for research purposes only under agreement from Massachusetts General Hospital. US patent 2022/0025254

Alternate Names for Serpin A4/Kallistatin Antibody [CoraFluor™ 1]

• antitrypsin), member 4
• KAL
• Kallistatin
• KLST
• KSTKallikrein inhibitor
• member 4
• PI-4
• PI4Peptidase inhibitor 4
• protease inhibitor 4 (kallistatin)
• serine (or cysteine) proteinase inhibitor, clade A (alpha-1 antiproteinase
• Serpin A4
• serpin peptidase inhibitor, clade A (alpha-1 antiproteinase, antitrypsin)

Background

Kallistatin inhibits human amidolytic and kininogenase activities of tissue kallikrein. Inhibition is achieved by formation of an equimolar, heat- and SDS-stable complex between the inhibitor and the enzyme, and generation of a small C-terminal fragment of the inhibi

Limitations

This product is for research use only and is not approved for use in humans or in clinical diagnosis. Primary Antibodies are guaranteed for 1 year from date of receipt.

Bioinformatics

• Gene Symbol: SERPINA4