SERF1A Antibody [DyLight 405]

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Product Details

Summary
Reactivity HuSpecies Glossary
Applications ICC/IF, IHC, IHC-P
Clonality
Polyclonal
Host
Rabbit
Conjugate
DyLight 405

SERF1A Antibody [DyLight 405] Summary

Immunogen
A synthetic peptide made to an internal portion of the human SERF1A protein (between residues 50-100) [UniProt O75920]
Localization
Nucleus, Cytoplasm.
Isotype
IgG
Clonality
Polyclonal
Host
Rabbit
Gene
SERF1A
Purity
Immunogen affinity purified
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Applications/Dilutions

Dilutions
  • Immunocytochemistry/Immunofluorescence
  • Immunohistochemistry
  • Immunohistochemistry-Paraffin
Application Notes
This SERF1A antibody is useful for Immunocytochemistry/Immunofluorescence and IHC-paraffin embedded sections. In ICC/IF, nuclear staining was observed in Ntera2 cells. In IHC-P, heavy nuclear staining and some cytoplasmic staining was seen in human Alzheimer's brain tissue. Prior to immunostaining paraffin tissues, antigen retrieval with sodium citrate buffer (pH 6.0) is recommended.

Reactivity Notes

Human

Packaging, Storage & Formulations

Storage
Store at 4C in the dark.
Buffer
50mM Sodium Borate
Preservative
0.05% Sodium Azide
Purity
Immunogen affinity purified

Notes

Dylight (R) is a trademark of Thermo Fisher Scientific Inc. and its subsidiaries. This conjugate is made on demand. Actual recovery may vary from the stated volume of this product. The volume will be greater than or equal to the unit size stated on the datasheet.

Alternate Names for SERF1A Antibody [DyLight 405]

  • FAM2B
  • h4F5
  • H4F5small EDRK-rich factor 1,4F5
  • Protein 4F5
  • SERF1
  • SMA modifier 1
  • small EDRK-rich factor 1A (telomeric)
  • SMAM1FAM2ASERF1B
  • spinal muscular atrophy-related gene H4F5

Background

SERF1A (small EDRK-rich factor 1A, SERF1, SERF1B, SMAM1) is the human ortholog of the C. elegans MOAG-4 gene. Although the function of the protein is not currently known, MOAG-4 was shown to be a positive regulator of protein aggregates. Inactivation of MOAG-4 leads to a rescue from proteotoxcity, and could play a role in human diseases such as Alzheimers disease and Parkinsons disease.

Limitations

This product is for research use only and is not approved for use in humans or in clinical diagnosis. Primary Antibodies are guaranteed for 1 year from date of receipt.

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Product General Protocols

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Video Protocols

ICC/IF Video Protocol

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Secondary Antibodies

 

Isotype Controls

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Bioinformatics

Gene Symbol SERF1A