SERF1A Antibody - BSA Free

Immunocytochemistry/Immunofluorescence: SERF1A Antibody [NBP1-78392] - Serf1a antibody was tested in Ntera2 cells with FITC (green). Nuclei were counterstained with DAPI (blue).

Immunohistochemistry: SERF1A Antibody [NBP1-78392] - Analysis of SERF1A in human Alzheimer's brain using DAB with hematoxylin counterstain.

• Reactivity: Hu
• Applications: ICC/IF, IHC
• Clonality: Polyclonal
• Host: Rabbit
• Conjugate: Unconjugated
• Format: BSA Free
• Concentration: 1.11 mg/ml

SERF1A Antibody - BSA Free Summary

• Description: Novus Biologicals Rabbit SERF1A Antibody - BSA Free (NBP1-78392) is a polyclonal antibody validated for use in IHC and ICC/IF. All Novus Biologicals antibodies are covered by our 100% guarantee.
• Immunogen: A synthetic peptide made to the N-terminal portion of the human SERF1A protein (between residues 1-60) [UniProt O75920]
• Localization: Nucleus, Cytoplasm.
• Isotype: IgG
• Clonality: Polyclonal
• Host: Rabbit
• Gene: SERF1A
• Purity: Immunogen affinity purified

Applications/Dilutions

• Dilutions:
  • Immunocytochemistry/ Immunofluorescence 1:100
  • Immunohistochemistry 1:600
  • Immunohistochemistry-Paraffin 1:600
• Application Notes: This SERF1A antibody is useful for Immunocytochemistry/Immunofluorescence and IHC-paraffin embedded sections. In ICC/IF, nuclear staining was observed in Ntera2 cells. In IHC-P, heavy nuclear staining and some cytoplasmic staining was seen in human Alzheimer's brain tissue. Prior to immunostaining paraffin tissues, antigen retrieval with sodium citrate buffer (pH 6.0) is recommended.

Packaging, Storage & Formulations

• Storage: Store at 4C short term. Aliquot and store at -20C long term. Avoid freeze-thaw cycles.
• Buffer: PBS and 30% Glycerol
• Preservative: 0.05% Sodium Azide
• Concentration: 1.11 mg/ml
• Purity: Immunogen affinity purified

Alternate Names for SERF1A Antibody - BSA Free

• FAM2B
• h4F5
• H4F5small EDRK-rich factor 1,4F5
• Protein 4F5
• SERF1
• SMA modifier 1
• small EDRK-rich factor 1A (telomeric)
• SMAM1FAM2ASERF1B
• spinal muscular atrophy-related gene H4F5

Background

SERF1A (small EDRK-rich factor 1A, SERF1, SERF1B, SMAM1) is the human ortholog of the C. elegans MOAG-4 gene. Although the function of the protein is not currently known, MOAG-4 was shown to be a positive regulator of protein aggregates. Inactivation of MOAG-4 leads to a rescue from proteotoxcity, and could play a role in human diseases such as Alzheimers disease and Parkinsons disease.

Limitations

This product is for research use only and is not approved for use in humans or in clinical diagnosis. Primary Antibodies are guaranteed for 1 year from date of receipt.

Bioinformatics

• Gene Symbol: SERF1A
• Entrez:
  • 8293(Human)
• Uniprot:
  • O75920(Human)