Senataxin Antibody (5D8)

Images

 
Immunohistochemistry-Paraffin: Senataxin Antibody (5D8) [NBP2-52727] - Senataxin antibody clone 5D8 was tested on human prostate tissue sections and generated strong cytoplasmic-nuclear staining in the secretary/basal ...read more
Flow Cytometry: Senataxin Antibody (5D8) [NBP2-52727] - An intracellular stain was performed on Jurkat cells with antibody NBP2-52727 (blue) and a matched isotype control (orange). Cells were fixed with 4% PFA and then ...read more
Flow (Intracellular): Senataxin Antibody (5D8) [NBP2-52727] - An intracellular stain was performed on HepG2 cells with antibody NBP2-52727 (blue) and a matched isotype control NBP2-27231 (orange). Cells were fixed with ...read more

Product Details

Summary
Reactivity HuSpecies Glossary
Applications Flow, Flow-IC, IHC, IHC-P
Clone
5D8
Clonality
Monoclonal
Host
Mouse
Conjugate
Unconjugated
Concentration
1.0 mg/ml

Order Details

Senataxin Antibody (5D8) Summary

Immunogen
Partial recombinant human Senataxin protein (between amino acids 2300-2600) [UniProt Q7Z333]
Clonality
Monoclonal
Host
Mouse
Gene
SETX
Purity
Protein A or G purified
Innovator's Reward
Test in a species/application not listed above to receive a full credit towards a future purchase.

Applications/Dilutions

Dilutions
  • Flow Cytometry 5 ug/mL
  • Immunohistochemistry 1:200 - 1:500
  • Immunohistochemistry-Paraffin 1:200 - 1:500
  • Flow (Intracellular) 5 ug/mL

Packaging, Storage & Formulations

Storage
Store at 4C short term. Aliquot and store at -20C long term. Avoid freeze-thaw cycles.
Buffer
PBS
Preservative
0.05% Sodium Azide
Concentration
1.0 mg/ml
Purity
Protein A or G purified

Alternate Names for Senataxin Antibody (5D8)

  • ALS4recessive, non-Friedreich type 1
  • AOA2FLJ43459
  • DKFZp781B151
  • KIAA0625FLJ12840
  • senataxin
  • SETX

Background

Senataxin (SETX, ALS4, AOA2, SCAR1) belongs to the DNA/NAM7 helicase family. The protein encoded for by Senataxin has a DNA/RNA helicase domain at its C-terminal end. Senataxin may play a role in RNA maturation. It may also be involved in DNA double-strand breaks damage response caused by oxidative stress. Cellular localization of Senataxin is limited to the nucleus and cytoplasm. Senataxin is abundantly expressed in skeletal muscle. Expression of Senataxin is also seen in heart, fibroblast, placenta, liver, and weakly in brain and lung. Post translational modifications of Senataxin include acetylation and phosphorylation. There are 3 known isoforms (302.9, 299.4 and 306.3 kDa).

Limitations

This product is for research use only and is not approved for use in humans or in clinical diagnosis. Primary Antibodies are guaranteed for 1 year from date of receipt.

Customers Who Viewed This Item Also Viewed...

MAB1368
Species: Hu, Mu
Applications: WB, Simple Western, CyTOF-ready, ICC, ICFlow, KO
NBP2-24915
Species: Hu, Mu, Rt, Bv
Applications: WB, IHC, IHC-P
NBP2-98661
Species: Hu
Applications: WB, ICC/IF, IHC, IHC-P
H00010097-M01
Species: Hu
Applications: WB, ELISA, IHC, IHC-P, S-ELISA
NB300-996
Species: Hu
Applications: WB, Flow, ICC/IF, IHC, IHC-P, PEP-ELISA
AF1436
Species: Mu
Applications: WB
NB100-885
Species: Hu, Mu
Applications: WB, ICC/IF, IHC, IHC-P, PEP-ELISA
NBP2-47594
Species: Hu
Applications: ICC/IF, IHC, IHC-P
NB100-565
Species: Hu, Mu, Rt
Applications: WB, ICC/IF, IHC, IHC-P, IP, KO
NBP2-75395
Species: Hu, Mu, Rt
Applications: WB, Flow, ICC/IF, IHC, IHC-P
AF5514
Species: Hu, Mu
Applications: WB
AF1444
Species: Mu
Applications: WB, IHC
MAB39102
Species: Hu
Applications: ICC
H00023435-M01
Species: Hu, Mu, Rt, Ba, Pp, I, Pm
Applications: WB, ELISA, Func, ICC/IF, IHC, IHC-P, IP, RNAi, S-ELISA
NBP1-82512
Species: Hu, Mu, Rt
Applications: WB, Simple Western, ICC/IF, IHC, IHC-P
NBP1-85533
Species: Hu
Applications: WB, ICC/IF, IHC, IHC-P
NBP1-84945
Species: Hu
Applications: WB, ICC/IF, IHC, IHC-P, KD
NBP2-94118
Species: Hu, Mu, Rt
Applications: WB, IHC
NBP2-52727
Species: Hu
Applications: Flow, Flow-IC, IHC, IHC-P

Publications for Senataxin Antibody (NBP2-52727) (0)

There are no publications for Senataxin Antibody (NBP2-52727).
By submitting your publication information earn gift cards and discounts for future purchases.

Reviews for Senataxin Antibody (NBP2-52727) (0)

There are no reviews for Senataxin Antibody (NBP2-52727). By submitting a review you will receive an Amazon e-Gift Card or Novus Product Discount.
  • Review with no image -- $10/€7/£6/$10 CAD/¥70 Yuan/¥1110 Yen
  • Review with an image -- $25/€18/£15/$25 CAD/¥150 Yuan/¥2500 Yen

Product General Protocols

Find general support by application which include: protocols, troubleshooting, illustrated assays, videos and webinars.

FAQs for Senataxin Antibody (NBP2-52727) (0)

There are no specific FAQs related to this product. Read our general customer & technical service FAQs.

Secondary Antibodies

 

Isotype Controls

Other Available Formats

Alexa Fluor 350 NBP2-52727AF350
Alexa Fluor 405 NBP2-52727AF405
Alexa Fluor 488 NBP2-52727AF488
Alexa Fluor 532 NBP2-52727AF532
Alexa Fluor 594 NBP2-52727AF594
Alexa Fluor 647 NBP2-52727AF647
Alexa Fluor 700 NBP2-52727AF700
Alexa Fluor 750 NBP2-52727AF750
Allophycocyanin NBP2-52727APC
Biotin NBP2-52727B
DyLight 350 NBP2-52727UV
DyLight 405 NBP2-52727V
DyLight 488 NBP2-52727G
DyLight 550 NBP2-52727R
DyLight 594 NBP2-52727DL594
DyLight 650 NBP2-52727C
DyLight 680 NBP2-52727FR
DyLight 755 NBP2-52727IR
FITC NBP2-52727F
HRP NBP2-52727H
Janelia Fluor 549 NBP2-52727JF549
Janelia Fluor 646 NBP2-52727JF646
PE NBP2-52727PE
PerCP NBP2-52727PCP

Additional Senataxin Products

Bioinformatics Tool for Senataxin Antibody (NBP2-52727)

Discover related pathways, diseases and genes to Senataxin Antibody (NBP2-52727). Need help? Read the Bioinformatics Tool Guide for instructions on using this tool.
Visit Tool

Diseases for Senataxin Antibody (NBP2-52727)

Discover more about diseases related to Senataxin Antibody (NBP2-52727).
 

Pathways for Senataxin Antibody (NBP2-52727)

View related products by pathway.

PTMs for Senataxin Antibody (NBP2-52727)

Learn more about PTMs related to Senataxin Antibody (NBP2-52727).
 

Research Areas for Senataxin Antibody (NBP2-52727)

Find related products by research area.

Blogs on Senataxin

There are no specific blogs for Senataxin, but you can read our latest blog posts.
Coronavirus Brochure

Customers Who Bought This Also Bought

Contact Information

Learn the difference between western blot and simple western

Product PDFs

Calculators

Concentration Calculator

The concentration calculator allows you to quickly calculate the volume, mass or concentration of your vial. Simply enter your mass, volume, or concentration values for your reagent and the calculator will determine the rest.

=
÷

Review this Product

Be the first to review our Senataxin Antibody (5D8) and receive a gift card or discount.

Bioinformatics

Gene Symbol SETX
Uniprot