SEC61B Antibody - BSA Free

Western Blot: SEC61B Antibody - BSA Free [NBP3-45409] - Mouse liver tissue were subjected to SDS PAGE followed by western blot with (SEC61B antibody) at dilution of 1:500

Immunohistochemistry: SEC61B Antibody - BSA Free [NBP3-45409] - Immunohistochemistry of paraffin-embedded human cervical cancer tissue slide using (SEC61B Antibody) at dilution of 1:50

• Reactivity: Hu, Mu
• Applications: WB, ELISA, ICC/IF, IHC
• Clonality: Polyclonal
• Host: Rabbit
• Conjugate: Unconjugated
• Format: BSA Free

SEC61B Antibody - BSA Free Summary

• Description: Novus Biologicals Rabbit SEC61B Antibody - BSA Free (NBP3-45409) is a polyclonal antibody validated for use in IHC, WB, ELISA and ICC/IF. All Novus Biologicals antibodies are covered by our 100% guarantee.
• Immunogen: Sec61 beta subunit. (Uniprot# P60468)
• Isotype: IgG
• Clonality: Polyclonal
• Host: Rabbit
• Gene: SEC61B
• Purity: Immunogen affinity purified

Applications/Dilutions

• Dilutions:
  • ELISA
  • Immunocytochemistry/ Immunofluorescence 1:20-1:200
  • Immunohistochemistry 1:20-1:200
  • Western Blot 1:1000-1:4000
• Theoretical MW: 10 kDa.
  Disclaimer note: The observed molecular weight of the protein may vary from the listed predicted molecular weight due to post translational modifications, post translation cleavages, relative charges, and other experimental factors.

Packaging, Storage & Formulations

• Storage: Store at -20C. Avoid freeze-thaw cycles.
• Buffer: PBS, 50% Glycerol, pH (7.3)
• Preservative: 0.02% Sodium Azide
• Purity: Immunogen affinity purified

Alternate Names for SEC61B Antibody - BSA Free

• protein translocation complex beta
• protein transport protein SEC61 beta subunit
• protein transport protein Sec61 subunit beta
• Sec61 beta subunit
• Sec61 complex, beta subunit
• SEC61B

Background

The SEC61 complex is the central component of the protein translocation apparatus of the endoplasmic reticulum (ER) membrane. Oligomers of the SEC61 complex form a transmembrane channel where proteins are translocated across and integrated into the ER membrane. This complex consists of three membrane proteins alpha, beta, and gamma. This gene encodes the beta subunit protein. The SEC61 subunits are also observed in the post ER compartment, suggesting that these proteins can escape the ER and recycle back. There is evidence for multiple polyadenylated sites for this transcript.

Limitations

This product is for research use only and is not approved for use in humans or in clinical diagnosis. Primary Antibodies are guaranteed for 1 year from date of receipt.

Bioinformatics

• Gene Symbol: SEC61B