SEC23IP Antibody

Western Blot: SEC23IP Antibody [NB100-1561] - Detection of Human Sec23IP(MSTP053) on HeLa whole cell lysate using NB100-1561.

• Reactivity: Hu
• Applications: WB, IP
• Clonality: Polyclonal
• Host: Rabbit
• Conjugate: Unconjugated
• Concentration: 0.2 mg/ml

SEC23IP Antibody Summary

• Description: Novus Biologicals Rabbit SEC23IP Antibody (NB100-1561) is a polyclonal antibody validated for use in WB and IP. Anti-SEC23IP Antibody: Cited in 2 publications. All Novus Biologicals antibodies are covered by our 100% guarantee.
• Immunogen: The immunogen recognized by this antibody maps to a region between residues 1 and 50 of human Sec23-Interacting Protein using the numbering given in entry NP_009121.1 (GeneID 11196).
• Isotype: IgG
• Clonality: Polyclonal
• Host: Rabbit
• Gene: SEC23IP
• Purity: Immunogen affinity purified

Applications/Dilutions

• Dilutions:
  • Immunoprecipitation 1-4 ug/mg of lysate
  • Western Blot 1:2500-1:10000
• Control:

  SEC23IP Overexpression Lysate

Packaging, Storage & Formulations

• Storage: Store at 4C. Do not freeze.
• Buffer: TBS and 0.1% BSA
• Preservative: 0.09% Sodium Azide
• Concentration: 0.2 mg/ml
• Purity: Immunogen affinity purified

Alternate Names for SEC23IP Antibody

• P125
• P125A
• SEC23 interacting protein
• SEC23-interacting protein

Background

Sec23IP is a protein found to interact with Sec23p which is part of COPII that coats vesicles involved in protein transport from the endoplasmic reticulum (ER) to the golgi. COPII consists of Sar 1p and two protein complexes made up of Sec23p-Sec24p, and Sec13p-Sec31p. It appears that Sec23IP makes an important contribution to the organization of ER exit sites. Alternate names for Sec23IP include p125 and MSTP053.

Limitations

This product is for research use only and is not approved for use in humans or in clinical diagnosis. Primary Antibodies are guaranteed for 1 year from date of receipt.

Publications for SEC23IP Antibody (NB100-1561)(2)

Publications using NB100-1561

• Perry MM, Moschos SA, Williams AE et al. Rapid Changes in MicroRNA-146a Expression Negatively Regulate the IL-1{beta}-Induced Inflammatory Response in Human Lung Alveolar Epithelial Cells. J Immunol;180(8):5689-98. 2008-04-15 [PMID: 18390754]
• Huttunen HJ, Guenette SY, Peach C et al. HtrA2 regulates beta-amyloid precursor protein (APP) metabolism through endoplasmic reticulum-associated degradation. J Biol Chem 2007-09-01 [PMID: 17684015]

Bioinformatics

• Gene Symbol: SEC23IP
• Entrez:
  • 11196(Human)
• Uniprot:
  • NP_009121.1(Human)