SEC23IP Products

Description

COPII-coated vesicles are involved in protein transport from the endoplasmic reticulum to the Golgi apparatus. The protein encoded by this gene was identified by its interaction with a mouse protein similar to yeast Sec23p, an essential component of the COPII. This protein shares significant similarity with phospholipid-modifying proteins, especially phosphatidic acid preferring-phospholipase A1. Overexpression of this protein has been shown to cause disorganization of the endoplasmic reticulum-Golgi intermediate compartment and Golgi apparatus, which suggests its role in the early secretory pathway.

Bioinformatics

Entrez	11196 Human
Uniprot	NP_009121 Human NP_009121.1 Human NM_007190 Human
Product By Gene ID	11196
Alternate Names	p125 SEC23-interacting protein P125A P125 SEC23 interacting protein

Diseases related to SEC23IP

Discover more about diseases related to SEC23IP.

Malignant Neoplasms
Stomach Neoplasms
Cell Transformation, Neoplastic
Neoplasm Metastasis
Superficial Spreading Malignant Melanoma Of Skin
Waardenburg Syndrome
Melanoma
Malignant Neoplasm Of Breast
Crest Syndrome
Carcinogenesis
Nodular Melanoma
Autistic Disorder
Tumor Angiogenesis
Malignant Neoplasm Of Stomach
Neoplasms
Pathologic Neovascularization

Pathways for SEC23IP

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Transport
Localization
Protein Transport
Secretory Pathway
Chylomicron Assembly
Fertilization
Cell Growth
Angiogenesis
Lipid Transport
Spermatogenesis
Secretion

Research Areas for SEC23IP

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Golgi Apparatus Markers

Bioinformatics Tool for SEC23IP

Discover related pathways, diseases and genes to SEC23IP. Need help? Read the Bioinformatics Tool Guide for instructions on using this tool.