SASS6 Antibody

Western Blot: SASS6 Antibody [H00163786-B01P] - Analysis of SASS6 expression in transfected 293T cell line by SASS6 polyclonal antibody. Lane 1: SASS6 transfected lysate(53.9 KDa). Lane 2: Non-transfected lysate.

• Reactivity: Hu, Mu, Ch
• Applications: WB, ICC/IF
• Clonality: Polyclonal
• Host: Mouse
• Conjugate: Unconjugated

SASS6 Antibody Summary

• Immunogen: SASS6 (AAI01027.1, 1 a.a. - 490 a.a.) full-length human protein. MQSLDDATKQLDFTRKTLAEKKQELDKLRNEWASHTAALTNKHSQELTNEKEKALQAQVQYQQQHEQQKKDLEILHQQNIHQLQNRLSELEVANKDLTERKYKGDSTIRELKAKLSGVEEELQRTKQEVLSLRRENSTLDVECHEKEKHVNQLQTKVAVLEQEIKDKDQLVLRTKEAFDTIQEQKVVLEENGEKNQVQLGKLEATIKSLSAELLKANEIIKKLQGDLKTLMGKLKLKNTVTIQQEKLLAEKEEKLQKEQKELQDVGQSLRIKEQEVCKLQEQLEATVKKLEESKQLLKNNEKLITWLNKELNENQLVRKQDVLGPSTTPPAHSSSNTIRSGISPNLNVVDGRLTYPTCGIGYPVSSAFAFQNTFPHSISAKNTSHPGSGTKVQFNLQFTKPNASLGDVQSGATISMPCSTDKENGENVGLESKYLKKREDSIPLRGLSQNLFSNSDHQRDGTLGALHTSSKPTALPSASSAYFPGQLPNS
• Specificity: SASS6 - spindle assembly 6 homolog (C. elegans),
• Isotype: IgG
• Clonality: Polyclonal
• Host: Mouse
• Gene: SASS6
• Purity: Protein A purified

Applications/Dilutions

• Dilutions:
  • Immunocytochemistry/Immunofluorescence
  • Western Blot 1:500
• Application Notes: Antibody reactive against Recombinant Protein with GST tag on ELISA and Western Blot and also on transfected lysate in western blot. GST tag alone is used as a negative control.

Packaging, Storage & Formulations

• Storage: Aliquot and store at -20C or -80C. Avoid freeze-thaw cycles.
• Buffer: PBS (pH 7.4)
• Preservative: No Preservative
• Purity: Protein A purified

Notes

This product is produced by and distributed for Abnova, a company based in Taiwan.

Alternate Names for SASS6 Antibody

• DKFZp761A078
• FLJ22097
• HsSAS-6
• MGC119440
• SAS-6
• SAS6hsSAS-6
• spindle assembly 6 homolog (C. elegans)
• spindle assembly abnormal protein 6 homolog

Background

SAS6 is necessary for centrosome duplication and functions during procentriole formation; SAS6 functions to ensure that each centriole seeds the formation of a single procentriole per cell cycle Strnad et al., (2007) [PubMed 17681132].[supplied by OMIM]

Limitations

This product is for research use only and is not approved for use in humans or in clinical diagnosis. Primary Antibodies are guaranteed for 1 year from date of receipt.

Publications for SASS6 Antibody (H00163786-B01P)(3)

Publications using H00163786-B01P

• Ogungbenro YA, Tena TC, Gaboriau D et al. Centrobin controls primary ciliogenesis in vertebrates. J Cell Biol 2018-02-13 [PMID: 29440264] (Human)
• Coelho PA, Bury L, Sharif B et al. Spindle Formation in the Mouse Embryo Requires Plk4 in the Absence of Centrioles. Dev Cell. 2013-11-21 [PMID: 24268700]
• Inanc B, Puetz M, Lalor P et al. Abnormal centrosomal structure and duplication in Cep135-deficient vertebrate cells. Mol Biol Cell. 2013-07-17 [PMID: 23864714]

Bioinformatics

• Gene Symbol: SASS6
• Entrez:
  • 163786(Human)
• Uniprot:
  • AAI01027.1(Human)