SAMSN1 Antibody (OTI7F5) [DyLight 650]

• Reactivity: Hu
• Applications: IHC
• Clone: OTI7F5
• Clonality: Monoclonal
• Host: Mouse
• Conjugate: DyLight 650

SAMSN1 Antibody (OTI7F5) [DyLight 650] Summary

• Immunogen: Recombinant protein fragment corresponding to amino acids 1-250 of human SAMSN1 (NP_071419) produced in E.coli.
• Isotype: IgG1
• Clonality: Monoclonal
• Host: Mouse
• Gene: SAMSN1
• Purity: Immunogen affinity purified

Applications/Dilutions

• Dilutions:
  • Immunohistochemistry
  • Immunohistochemistry-Paraffin
• Application Notes: Optimal dilution of this antibody should be experimentally determined.

Packaging, Storage & Formulations

• Storage: Store at 4C in the dark.
• Buffer: 50mM Sodium Borate
• Preservative: 0.05% Sodium Azide
• Purity: Immunogen affinity purified

Notes

DyLight (R) is a trademark of Thermo Fisher Scientific Inc. and its subsidiaries.

Alternate Names for SAMSN1 Antibody (OTI7F5) [DyLight 650]

• HACS1gene with homology to KIAA0790 protein10NASH1
• Hematopoietic adaptor containing SH3 and SAM domains 1
• SAM and SH3 domain containing 1
• SAM and SH3 domain containing 2
• SAM domain, SH3 domain and nuclear localisation signals, 1
• SAM domain, SH3 domain and nuclear localization signals 1
• SAM domain, SH3 domain and nuclear localization signals protein 1
• SAM domain-containing protein SAMSN-1
• SH3D6B
• SH3-SAM adaptor protein

Background

SAMSN1 is a member of a novel gene family of putative adaptors and scaffold proteins containing SH3 and SAM (sterile alpha motif) domains. It also contains several predicted consensus nuclear localization signals and a tyrosine kinase phosphorylation motif. Northern blot analysis has revealed expression of a 2.2kb SAMSN1 transcript in human immune tissues and hematopoietic cell types including normal bone marrow, acute myeloid leukemia, and multiple myeloma; low-level expression was seen in other tissues such as heart, brain, placenta, and lung. SAMSN1 has been shown to be up-regulated by B cell activation signals and is a participant in B cell activation and differentiation.

Limitations

This product is for research use only and is not approved for use in humans or in clinical diagnosis. Primary Antibodies are guaranteed for 1 year from date of receipt.

Bioinformatics

• Gene Symbol: SAMSN1