Species: Hu
Applications: WB, ICC/IF, IHC
Host: Rabbit Polyclonal
Species: Hu
Applications: WB, ICC/IF, IHC
Host: Rabbit Polyclonal
Species: Hu
Applications: WB, IHC
Host: Mouse Monoclonal
Species: Hu
Applications: WB
Species: Hu
Applications: PAGE
Species: Hu
Applications: AC
Species: Hu
Applications: AC
Description
SAMSN1 is a member of a novel gene family of putative adaptors and scaffold proteins containing SH3 and SAM (sterile alpha motif) domains. It also contains several predicted consensus nuclear localization signals and a tyrosine kinase phosphorylation motif. Northern blot analysis has revealed expression of a 2.2kb SAMSN1 transcript in human immune tissues and hematopoietic cell types including normal bone marrow, acute myeloid leukemia, and multiple myeloma; low-level expression was seen in other tissues such as heart, brain, placenta, and lung. SAMSN1 has been shown to be up-regulated by B cell activation signals and is a participant in B cell activation and differentiation.
Bioinformatics
Entrez |
Human |
Uniprot |
Human Human Human Human |
Product By Gene ID |
64092 |
Alternate Names |
- HACS1gene with homology to KIAA0790 protein10NASH1
- Hematopoietic adaptor containing SH3 and SAM domains 1
- SAM and SH3 domain containing 1
- SAM and SH3 domain containing 2
- SAM domain, SH3 domain and nuclear localisation signals, 1
- SAM domain, SH3 domain and nuclear localization signals 1
- SAM domain, SH3 domain and nuclear localization signals protein 1
- SAM domain-containing protein SAMSN-1
- SH3D6B
- SH3-SAM adaptor protein
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Research Areas for SAMSN1
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Stem Cell Markers