S1P1/EDG-1 Products

Antibodies
S1P1/EDG-1 Antibody
S1P1/EDG-1 Antibody
NB120-11424
Species: Hu, Mu, Rt
Applications: WB, ICC/IF, IHC, IHC-P, IP
Host: Rabbit Polyclonal
Lysates
S1P1/EDG-1 Overexpression Lys ...
S1P1/EDG-1 Overexpression Lysate (...
NBP2-04197
Applications: WB
S1P1/EDG-1 Overexpression Lys ...
S1P1/EDG-1 Overexpression Lysate (...
H00001901-T01
Species: Hu
Applications: WB
Proteins
Recombinant Human S1P1/EDG-1 ...
Recombinant Human S1P1/EDG-1 Protein
H00001901-P01
Species: Hu
Applications: WB, ELISA, PA
S1P1/EDG-1 Recombinant Protei ...
S1P1/EDG-1 Recombinant Protein Ant...
NBP2-58024PEP
Species: Hu
Applications: B/N, Ctrl
Recombinant Human S1P1/EDG-1 ...
Recombinant Human S1P1/EDG-1 Protein
H00001901-Q01
Species: Hu
Applications: WB, ELISA, PA
RNAi
S1P1/EDG-1 RNAi
S1P1/EDG-1 RNAi
H00001901-R02
Species: Hu
Applications: RNAi, RNAi SP

Description

EBP 50 [ERM (ezrin-radixin-moesin) binding phosphoprotein of 50 kDa] is a PDZ containing protein that is involved in the linkage of integral membrane proteins to the cytoskeleton. EBP50 contains two tandem PDZ domains followed by a carboxy-terminal sequence that binds to members of the ERM family of membrane-cytoskeleton adaptors. The PDZ domains within EBP50 bind to the carboxy termini of such target proteins as beta2 adrenergic receptor, platelet-derived growth factor receptor (PDGFR), and the cystic fibrosis conductance regulator (CFTR). The PDZ domains are also believed to be involved in the oligomerization of EBP 50 to form multiprotein complexes which helps to facilitate the formation of functional signalling complexes. EBP 50 has been shown to link integral membrane proteins to the cytoskeleton by binding to members of the ERM family of proteins, which bind to F-actin. Through these interactions, EBP 50 is implicated in the localization of interactive groups of proteins into subcellular domains and in the regulation of activity of those interacting proteins. Immunohistochemical studies have shown that EBP 50 is found exclusively at the apical membranes of epithelial cells.

Bioinformatics

Entrez Human
Mouse
Rat
Uniprot Human
Human
Human
Human
Mouse
Product By Gene ID 1901
Alternate Names
  • CD363
  • s1p1
  • S1P receptor 1
  • CD363 antigen
  • CHEDG1
  • sphingosine 1-phosphate receptor EDG1
  • Sphingosine 1-phosphate receptor Edg-1
  • sphingosine 1-phosphate receptor 1
  • Endothelial differentiation G-protein coupled receptor 1
  • FLJ58121
  • endothelial differentiation, sphingolipid G-protein-coupled receptor, 1
  • EDG-1
  • D1S3362
  • S1P1ECGF1
  • EDG1edg-1
  • S1P receptor Edg-1
  • sphingosine-1-phosphate receptor 1

Research Areas for S1P1/EDG-1

Find related products by research area and learn more about each of the different research areas below.

Cancer
Cytoskeleton Markers
GPCR
Lipid and Metabolism
Neuroscience
Signal Transduction

PTMs for S1P1/EDG-1

Learn more about PTMs related to S1P1/EDG-1.

Phosphorylation
Cleavage
Glycosylation
Methylation

Bioinformatics Tool for S1P1/EDG-1

Discover related pathways, diseases and genes to S1P1/EDG-1. Need help? Read the Bioinformatics Tool Guide for instructions on using this tool.
 
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