S1P1/EDG-1 Antibody (218713) [Phycoerythrin]

• Applications: Flow
• Clone: 218713
• Clonality: Monoclonal
• Host: Mouse
• Conjugate: Phycoerythrin

S1P1/EDG-1 Antibody (218713) [Phycoerythrin] Summary

• Additional Information: Clone 218713 was used by HLDA to establish CD designation
• Immunogen: NS0 mouse myeloma cell line transfected with human S1P₁/EDG‑1
  Met1-Ser382
  Accession # P21453
• Specificity: Detects human S1P₁/EDG‑1 by flow cytometry.
• Source: N/A
• Isotype: IgG2b
• Clonality: Monoclonal
• Host: Mouse
• Gene: S1PR1
• Purity Statement: Protein A or G purified from hybridoma culture supernatant

Packaging, Storage & Formulations

• Storage: Protect from light. Do not freeze.
  • 12 months from date of receipt, 2 to 8 °C as supplied.
• Buffer: Supplied in a saline solution containing BSA and Sodium Azide.
• Preservative: Sodium Azide

Notes

This product is produced by and ships from R&D Systems, Inc., a Bio-Techne brand.

Background

S1P₁, also known as EDG-1, is a member of the endothelial differentiation gene family. It is a high affinity G protein-coupled receptor for the bioactive lipid, Sphingosine-1-phosphate. S1P₁ signaling regulates endothelial cell survival, cytoskeletal remodeling, chemotaxis, and angiogenesis.

Limitations

This product is for research use only and is not approved for use in humans or in clinical diagnosis. Primary Antibodies are guaranteed for 1 year from date of receipt.

Bioinformatics

• Gene Symbol: S1PR1