S100A6 Antibody [Alexa Fluor® 750]

• Reactivity: Hu, Mu
• Applications: WB, IHC, KO
• Clonality: Polyclonal
• Host: Sheep
• Conjugate: Alexa Fluor 750

S100A6 Antibody [Alexa Fluor® 750] Summary

• Immunogen: E. coli-derived recombinant mouse S100A6
  Met1-Lys89
  Accession # P14069
• Specificity: Detects human and mouse S100A6 in direct ELISAs and Western blots. In direct ELISAs, less than 2% cross-reactivity with recombinant mouse S100A1 and recombinant mouse S100A4 is observed.
• Isotype: IgG
• Clonality: Polyclonal
• Host: Sheep
• Purity Statement: Antigen Affinity-purified

Applications/Dilutions

• Dilutions:
  • Immunohistochemistry
  • Knockout Validated
  • Western Blot

Packaging, Storage & Formulations

• Storage: Protect from light. Do not freeze. 12 months from date of receipt, 2 to 8 °C as supplied
• Buffer: Supplied 0.2mg/ml in 1X PBS with RDF1 and 0.09% Sodium Azide

Notes

This product is produced by and ships from R&D Systems, Inc., a Bio-Techne brand.

Alternate Names for S100A6 Antibody [Alexa Fluor® 750]

• 2A9
• CABP
• CACY
• CACY5B10
• calcyclin
• Growth factor-inducible protein 2A9
• MLN 4
• PRA
• PRAS100 calcium binding protein A6 (calcyclin)
• Prolactin receptor-associated protein
• protein S100-A6
• S100 calcium binding protein A6
• S100 calcium-binding protein A6 (calcyclin)
• S100 calcium-binding protein A6
• S100A6

Background

Mouse S100A6 (also prolactin receptor-associated protein and calcyclin) is a 10 kDa member of the S100 family of calcium-binding proteins. S100A6 is 89 amino acids (aa) in length and contains two calcium-binding EF-hand domains (aa 12‑47 and 48‑83). Intracellularly, S100A6 will both noncovalently homodimerize and heterodimerize with S100B plus SGT1. Extracellularly, it is secreted via a noncanonical pathway and binds to RAGE, inducing apoptosis. It is expressed by neurons, endothelium, fibroblasts and glandular epithelia. Mouse S100A6 is 99% and 96% aa identical to rat and human S100A6, respectively.

Limitations

This product is for research use only and is not approved for use in humans or in clinical diagnosis. Primary Antibodies are guaranteed for 1 year from date of receipt.