ROR1 Antibody - Humanized, (Research Grade zilovertamab Biosimilar) - Low Endotoxin, Azide and BSA Free

Immobilized human ROR1 His at 2 ug/mL can bind ROR1 Antibody (zilovertamab) - Humanized, EC50=0.00283 ug/mL.

zilovertamab by Human ROR1 HEK293T cells increased with the increase of antibody concentration, and the Internalization Rate (%) reached 72%.

A549 cells were stained with ROR1 Antibody (zilovertamab) - Humanized and negative control protein respectively, washed and then followed by PE and analyzed with FACS, EC50=0.002776 ug/ml.

• Reactivity: Hu
• Applications: ELISA, Flow, Func
• Clonality: Monoclonal
• Host: Human
• Conjugate: Unconjugated
• Format: Low Endotoxin, Azide and BSA Free
• Concentration: LYOPH

ROR1 Antibody - Humanized, (Research Grade zilovertamab Biosimilar) - Low Endotoxin, Azide and BSA Free Summary

• Description: The heavy chain type is huIgG1, and the light chain type is hukappa. It has a predicted MW of 146.14 kDa.
  
  Also known as 'zilovertamab'.
  
  This product is shipped at ambient temperature. Upon receipt, store immediately at -20C or lower for 12 months in a lyophilized state. - 80C for 3 months after reconstitution. Avoid repeated freeze-thaw cycles.
• Additional Information: Recombinant Monoclonal Antibody
• Immunogen: ROR1
• Source: CHO
• Isotype: IgG1
• Clonality: Monoclonal
• Host: Human
• Gene: ROR1
• Purity: Protein A purified
• Endotoxin Note: < 0.001EU/ug,determined by LAL method.

Applications/Dilutions

• Dilutions:
  • ELISA
  • Flow Cytometry
  • Functional

Packaging, Storage & Formulations

• Storage: Store at -20C in powder form. Store at -80C once reconstituted.
• Buffer: Lyophilized from 25mM histidine, 8% sucrose, 0.01% Tween80 (pH6.2)
• Preservative: No Preservative
• Concentration: LYOPH
• Purity: Protein A purified
• Reconstitution Instructions: Reconstitute with sterile, distilled water to a final concentration of 1 mg/ml. Gently shake to solubilize completely. Do not vortex.

Alternate Names for Array

• EC 2.7.10.1
• MGC99659
• neurotrophic tyrosine kinase receptor-related 1
• Neurotrophic tyrosine kinase, receptor-related 1
• NTRKR1
• NTRKR1dJ537F10.1
• receptor tyrosine kinase-like orphan receptor 1
• ROR1
• tyrosine-protein kinase transmembrane receptor ROR1

Background

ROR1 is encoded by this gene is a receptor protein tyrosine kinase that modulates neurite growth in the central nervous system. It is a type I membrane protein and belongs to the ROR subfamily of cell surface receptors. Alternative splicing results in multiple transcript variants encoding different isoforms.

Limitations

This product is for research use only and is not approved for use in humans or in clinical diagnosis. Primary Antibodies are guaranteed for 1 year from date of receipt.

Bioinformatics

• Gene Symbol: ROR1
• Uniprot:
  • Q01973()