RELM beta Antibody (250911) [Unconjugated]

• Reactivity: Hu
• Applications: ELISA
• Clone: 250911
• Clonality: Monoclonal
• Host: Mouse
• Conjugate: Unconjugated
• Concentration: LYOPH

RELM beta Antibody (250911) [Unconjugated] Summary

• Immunogen: E. coli-derived recombinant human RELM beta
  Gly21-Thr111
  Accession # Q9BQ08
• Specificity: Detects human RELM beta in direct ELISAs. Does not cross-react with recombinant mouse (rm) RELM alpha , rmRELM beta , recombinant rat RELM gamma , or rmResistin. Not recommended for natural lysates in Western blot.
• Source: N/A
• Isotype: IgG1
• Clonality: Monoclonal
• Host: Mouse
• Gene: RETNLB
• Purity Statement: Protein A or G purified from hybridoma culture supernatant

Applications/Dilutions

• Dilutions:
  • ELISA

Packaging, Storage & Formulations

• Storage: Use a manual defrost freezer and avoid repeated freeze-thaw cycles.
  • 12 months from date of receipt, -20 to -70 °C as supplied.
  • 1 month, 2 to 8 °C under sterile conditions after reconstitution.
  • 6 months, -20 to -70 °C under sterile conditions after reconstitution.
• Buffer: Lyophilized from a 0.2 μm filtered solution in PBS with Trehalose. *Small pack size (SP) is supplied either lyophilized or as a 0.2 µm filtered solution in PBS.
• Preservative: No Preservative
• Concentration: LYOPH
• Reconstitution Instructions: Reconstitute at 0.5 mg/mL in sterile PBS.

Notes

This product is produced by and ships from R&D Systems, Inc., a Bio-Techne brand.

Alternate Names for RELM beta Antibody (250911) [Unconjugated]

• C/EBP-epsilon regulated myeloid-specific secreted cysteine-rich proteinprecursor 2
• CCRG
• Colon and small intestine-specific cysteine-rich protein
• Colon carcinoma-related gene protein
• cysteine-rich secreted A12-alpha-like protein 1
• Cysteine-rich secreted protein A12-alpha-like 1
• Cysteine-rich secreted protein FIZZ2
• FIZZ1
• FIZZ2RELM-beta
• found in inflammatory zone 1
• HXCP2XCP2
• RELM beta
• RELMb
• RELMbeta
• resistin like beta
• resistin-like beta
• RETNL2

Background

Resistin-like molecule beta (RELM beta , also known as Found in Inflammatory Zone 2 (FIZZ2), is a homodimeric protein belonging to the RELM/FIZZ family of cysteine rich secretory proteins. RELM beta secretion by intestinal goblet cells is induced by Th2 cytokines in response to nematode infections.

Limitations

This product is for research use only and is not approved for use in humans or in clinical diagnosis. Primary Antibodies are guaranteed for 1 year from date of receipt.

Publications for RELM beta Antibody (MAB2917)(3)

Publications using MAB2917

• TB Tsay, PH Chen, LW Chen Aryl hydrocarbon receptor ligands enhance lung immunity through intestinal IKK β pathways J Transl Med, 2019-09-05;17(1):304. 2019-09-05 [PMID: 31488203] (Western Blot, Mouse)
• Wu Y, Hsu C, Chen P, Fung C, Chen L Toll-like receptor stimulation induces nondefensin protein expression and reverses antibiotic-induced gut defense impairment. Infect Immun, 2014-03-04;82(5):1994-2005. 2014-03-04 [PMID: 24595141] (Western Blot, Mouse)
• Angelini DJ, Su Q, Yamaji-Kegan K, Fan C, Teng X, Hassoun PM, Yang SC, Champion HC, Tuder RM, Johns RA Resistin-like molecule-beta in scleroderma-associated pulmonary hypertension. Am. J. Respir. Cell Mol. Biol., 2009-02-27;41(5):553-61. 2009-02-27 [PMID: 19251945] (Western Blot, Human)

Bioinformatics

• Gene Symbol: RETNLB
• Uniprot:
  • Q9BQ08()