RB1 Antibody (XZ91) - BSA Free

• Reactivity: Hu, Mu, Rt, Ch, Ma-Mn
• Applications: WB, IP
• Clone: XZ91
• Clonality: Monoclonal
• Host: Mouse
• Conjugate: Unconjugated
• Format: BSA Free

RB1 Antibody (XZ91) - BSA Free Summary

• Description: Novus Biologicals Mouse RB1 Antibody (XZ91) - BSA Free (NBP3-30762) is a monoclonal antibody validated for use in WB and IP. All Novus Biologicals antibodies are covered by our 100% guarantee.
• Immunogen: A recombinant protein corresponding to amino acids 387 to 928 of the human retinoblastoma sequence
• Isotype: IgG1
• Clonality: Monoclonal
• Host: Mouse
• Gene: RB1
• Purity: Protein A or G purified

Applications/Dilutions

• Dilutions:
  • Immunoprecipitation
  • Western Blot
• Application Notes: .

Packaging, Storage & Formulations

• Storage: Store at -20C. Avoid freeze-thaw cycles.
• Buffer: Phosphate buffered saline
• Preservative: 0.08% Sodium Azide
• Purity: Protein A or G purified

Alternate Names for RB1 Antibody (XZ91) - BSA Free

• OSRC
• osteosarcoma
• p105-Rb
• pp110
• pRb
• RB
• RB1
• retinoblastoma 1
• retinoblastoma suspectibility protein
• retinoblastoma-associated protein

Background

Rb is a tumor suppressor nuclear phosphoprotein capable of binding to DNA. It is phosphorylated on serine and threonine, but not on tyrosine residues. It forms a complex with SV40 large T antigen, adenovirus E1A, and human papilloma virus-16 E. Rb protein may act by regulating transcription and loss of ts function leads to uncontrolled cell growth. Aberrations in the RB gene have been implicated in cancers of breast, colon, prostate, kidney, nasopharynx, and leukemia.

Limitations

This product is for research use only and is not approved for use in humans or in clinical diagnosis. Primary Antibodies are guaranteed for 1 year from date of receipt.

Bioinformatics

• Gene Symbol: RB1