Rat CXCL3/CINC-2 alpha/beta Quantikine ELISA Kit

• Reactivity: Rt
• Applications: ELISA
• Conjugate: HRP

Rat CXCL3/CINC-2 alpha/beta Quantikine ELISA Kit Summary

• Background: The Quantikine Rat CINC-2 alpha/beta Immunoassay is a 4.5 hour solid-phase ELISA designed to measure rat CINC-2 alpha/beta in cell culture supernates, serum, and plasma. It contains E. coli-expressed recombinant rat CINC-2 alpha and antibodies raised against the recombinant factor. This immunoassay has been shown to accurately quantitate recombinant rat CINC-2 alpha and recombinant ...rat CINC-2 beta. Results obtained using natural rat CINC-2 aalph/beta showed linear curves that were parallel to the standard curves obtained using the Quantikine kit standards. These results indicate that this kit can be used to determine relative mass values for naturally occurring rat CINC-2 alpha/beta.
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• Specificity: Natural and recombinant rat CINC-2 alpha/beta
• Source: N/A
• Assay Type: Solid Phase Sandwich ELISA
• Inter-Assay: See PDF Datasheet for details
• Intra-Assay: See PDF Datasheet for details
• Spike Recovery: See PDF Datasheet for details
• Sample Volume: See PDF Datasheet for details
• Gene: Cxcl3

Applications/Dilutions

• Dilutions:
  • ELISA
• Application Notes: No significant interference observed with available related molecules.

Packaging, Storage & Formulations

• Storage: Store the unopened product at 2 - 8 °C. Do not use past expiration date.

Notes

This product is produced by and ships from R&D Systems, Inc., a Bio-Techne brand.

Alternate Names for Rat CXCL3/CINC-2 alpha/beta Quantikine ELISA Kit

• chemokine (C-X-C motif) ligand 3
• CINC-2
• CINC-2b
• C-X-C motif chemokine 3
• CXCL3
• Dcip1
• Gm1960
• GRO gamma
• GRO3 oncogene
• GRO3
• GROG
• GRO-gamma
• GRO-gamma(1-73)
• Growth-regulated protein gamma
• Macrophage inflammatory protein 2-beta
• melanoma growth stimulatory activity gamma
• MGSA gamma
• MIP2B
• MIP-2b
• MIP2-beta
• SCYB3

Background

CXCL3/GRO gamma, also known as DCIP-1 in mouse and CINC-2 in rat, is a member of the CXC chemokine family. Human CXCL3/GRO gamma is 107 amino acids (aa) in length, which includes a proposed signal peptide (aa 1–34), with a predicted molecular weight of 11 kDa. The mouse and rat orthologs share 65% and 59% aa sequence identity with the human protein, respectively. Genome-wide analysis suggests that the protein encoded by the mouse Cxcl1 gene is homologous to human CXCL3/GRO gamma protein. CXCL3/GRO gamma is chemotactic for granulocytes, including neturophils.

⚠ WARNING: This product can expose you to chemicals including N,N-Dimethylforamide, which is known to the State of California to cause cancer. For more information, go to www.P65Warnings.ca.gov.

Publications for CXCL3/GRO gamma/CINC-2/DCIP-1 (RCN200)(4)

Publications using RCN200

• C Nishida, H Izumi, T Tomonaga, KY Wang, H Higashi, JI Takeshita, R Ono, K Sumiya, S Fujii, Y Hata, K Sakurai, Y Higashi, K Yamasaki, K Yatera, Y Morimoto Effect of Different Molecular Weights of Polyacrylic Acid on Rat Lung Following Intratracheal Instillation International Journal of Molecular Sciences, 2022-09-07;23(18):. 2022-09-07 [PMID: 36142256] (Rat)
• F Rohn, C Kordes, T Buschmann, D Reichert, M Wammers, G Poschmann, K Stühler, AS Benk, F Geiger, JP Spatz, D Häussinger Impaired integrin &alpha5 /&beta1 -mediated hepatocyte growth factor release by stellate cells of the aged liver Aging Cell, 2020-03-11;0(0):e13131. 2020-03-11 [PMID: 32157808] (Rat)
• T Tomonaga, H Izumi, Y Yoshiura, T Myojo, T Oyabu, BW Lee, T Okada, Y Li, K Kawai, T Higashi, Y Morimoto Assessment of Pulmonary Toxicity Induced by Inhaled Toner with External Additives Biomed Res Int, 2017-01-16;2017(0):4245309. 2017-01-16 [PMID: 28191462] (Mouse)
• Stevenson CS, Docx C, Webster R, Battram C, Hynx D, Giddings J, Cooper PR, Chakravarty P, Rahman I, Marwick JA, Kirkham PA, Charman C, Richardson DL, Nirmala NR, Whittaker P, Butler K Comprehensive gene expression profiling of rat lung reveals distinct acute and chronic responses to cigarette smoke inhalation. Am. J. Physiol. Lung Cell Mol. Physiol., 2007-08-24;293(5):L1183-93. 2007-08-24 [PMID: 17720875] (Rat)

Bioinformatics

• Gene Symbol: Cxcl3