Rat CXCL3/CINC-2 alpha/beta DuoSet ELISA, 15 Plate

• Reactivity: Rt
• Applications: ELISA
• Conjugate: Biotin

Rat CXCL3/CINC-2 alpha/beta DuoSet ELISA, 15 Plate Summary

• Source: N/A
• Assay Type: Solid Phase Sandwich ELISA
• Inter-Assay: See PDF Datasheet for details
• Intra-Assay: See PDF Datasheet for details
• Spike Recovery: See PDF Datasheet for details
• Sample Volume: See PDF Datasheet for details
• Gene: Cxcl3

Applications/Dilutions

• Dilutions:
  • ELISA
• Application Notes: No significant interference observed with available related molecules.

Packaging, Storage & Formulations

• Storage: Store the unopened product at 2 - 8 °C. Do not use past expiration date.

Notes

This product is produced by and ships from R&D Systems, Inc., a Bio-Techne brand.

Alternate Names for Rat CXCL3/CINC-2 alpha/beta DuoSet ELISA, 15 Plate

• chemokine (C-X-C motif) ligand 3
• CINC-2
• CINC-2b
• C-X-C motif chemokine 3
• CXCL3
• Dcip1
• Gm1960
• GRO gamma
• GRO3 oncogene
• GRO3
• GROG
• GRO-gamma
• GRO-gamma(1-73)
• Growth-regulated protein gamma
• Macrophage inflammatory protein 2-beta
• melanoma growth stimulatory activity gamma
• MGSA gamma
• MIP2B
• MIP-2b
• MIP2-beta
• SCYB3

Background

CXCL3/GRO gamma, also known as DCIP-1 in mouse and CINC-2 in rat, is a member of the CXC chemokine family. Human CXCL3/GRO gamma is 107 amino acids (aa) in length, which includes a proposed signal peptide (aa 1–34), with a predicted molecular weight of 11 kDa. The mouse and rat orthologs share 65% and 59% aa sequence identity with the human protein, respectively. Genome-wide analysis suggests that the protein encoded by the mouse Cxcl1 gene is homologous to human CXCL3/GRO gamma protein. CXCL3/GRO gamma is chemotactic for granulocytes, including neturophils.

Publications for CXCL3/GRO gamma/CINC-2/DCIP-1 (DY516)(4)

Publications using DY516

• VGB Brito, MS Patrocinio, MCL Sousa, AEA Barreto, SCT Frasnelli, VS Lara, CF Santos, SHP Oliveira Mast cells contribute to alveolar bone loss in Spontaneously Hypertensive Rats with periodontal disease regulating cytokines production PLoS ONE, 2021-03-04;16(3):e0247372. 2021-03-04 [PMID: 33661916] (Rat)
• L Gifre-Reno, E Ugarte-Ber, E Martens, L Boon, O Cano-Garri, E Martínez-N, T Luque, R Roca-Pinil, Ò Conchillo-, N Ferrer-Mir, A Villaverde, G Opdenakker, E Garcia-Fru, A Arís Recombinant Protein-Based Nanoparticles: Elucidating their Inflammatory Effects In Vivo and their Potential as a New Therapeutic Format Pharmaceutics, 2020-05-13;12(5):. 2020-05-13 [PMID: 32414218] (Mouse)
• Birrell MA, McCluskie K, Hardaker E, Knowles R, Belvisi MG Utility of exhaled nitric oxide as a noninvasive biomarker of lung inflammation in a disease model. Eur. Respir. J., 2006-09-27;28(6):1236-44. 2006-09-27 [PMID: 17005583] (Rat)
• Watts JA, Zagorski J, Gellar MA, Stevinson BG, Kline JA Cardiac inflammation contributes to right ventricular dysfunction following experimental pulmonary embolism in rats. J. Mol. Cell. Cardiol., 2006-06-30;41(2):296-307. 2006-06-30 [PMID: 16814320] (Rat)

FAQs for CXCL3/GRO gamma/CINC-2/DCIP-1 (DY516). (Showing 1 - 1 of 1 FAQs).

1. What is the difference between the Quantikine and Duoset ELISA kits?
   • Our Quantikine kits are fully optimized and validated for the sample types listed on the product specific webpage and datasheet, as this can vary between kits. Each kit is supplied ready to use with one pre-coated 96-well plate, a detection antibody directly conjugated to HRP, and all other necessary reagents. These kits are ideal for researchers who want the convenience of a ready to use and optimized ELISA product. Some of these kits are also available prepackaged in larger 6 and 50 plate sizes.Our DuoSet Kits, in contrast, are ELISA development kits containing the capture and detection antibody, the mass-value calibrated standard, and streptavidin-HRP to prepare approximately 5 or 15 plates. Ancillary reagents will need to be used/purchased, and for most kits, we will recommend one of our Ancillary Reagent Kits, which contain the reagents we use ourselves in-house. DuoSet kits are validated only for cell culture supernatant samples and therefore require further development and validation for accurate measurement in more complex samples such as serum and plasma. Our DuoSet Kits offer an economical, flexible alternative for the experienced ELISA user.

Bioinformatics

• Gene Symbol: Cxcl3