RASGRP3 Antibody

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Product Details

Summary
Product Discontinued
View other related RASGRP3 Primary Antibodies

Order Details


    • Catalog Number
      NB300-966
    • Availability
      Product Discontinued

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RASGRP3 Antibody Summary

Immunogen
Sythetic peptide GSSGLGKAATLDE-C, representing the N-Terminus of the human protein sequence according to NP_733772.
Clonality
Polyclonal
Host
Goat
Gene
RASGRP3
Purity
Immunogen affinity purified
Innovator's Reward
Test in a species/application not listed above to receive a full credit towards a future purchase.

Applications/Dilutions

Dilutions
  • Peptide ELISA 1:32000
Application Notes
Preliminary experiments gave an approx 48kDa band in Human Brain and Kidney lysates.
Positive Control
RASGRP3 Lysate (NBL1-15171)

Reactivity Notes

Cross reacts with Human. Expected from sequence similarity: Mouse, Rat, Dog, Pig and Cow.

Packaging, Storage & Formulations

Storage
Store at -20C. Avoid freeze-thaw cycles.
Buffer
0.5 mg/ml Tris (pH 7.3) and 0.5% BSA
Preservative
0.02% Sodium Azide
Concentration
0.5 mg/ml
Purity
Immunogen affinity purified

Notes

Please note, this antibody is considered Innovators Grade. Innovators Grade antibodies are generally unvalidated and require additional characterization for most new species/applications. Novus has made these antibodies available through our Innovators Reward program. Complete an online review with image, detailing your positive or negative results. In return, you receive a discount voucher for 100% of the purchase price of the reviewed product. Please contact us at innovators@novusbio.com for more details.

Alternate Names for RASGRP3 Antibody

  • Calcium and DAG-regulated guanine nucleotide exchange factor III
  • GRP3KIAA0846ras guanyl-releasing protein 3
  • Guanine nucleotide exchange factor for Rap1
  • RAS guanyl releasing protein 3 (calcium and DAG-regulated)

Background

Members of the RAS (see HRAS; MIM 190020) subfamily of GTPases function in signal transduction as GTP/GDP-regulated switches that cycle between inactive GDP- and active GTP-bound states. Guanine nucleotide exchange factors (GEFs), such as RASGRP3, serve as RAS activators by promoting acquisition of GTP to maintain the active GTP-bound state and are the key link between cell surface receptors and RAS activation (Rebhun et al., 2000).[supplied by OMIM]

Limitations

This product is for research use only and is not approved for use in humans or in clinical diagnosis. Primary Antibodies are guaranteed for 1 year from date of receipt.

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Positive Control Lysate(s)

Secondary Antibodies

 

Isotype Controls

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Bioinformatics

Gene Symbol RASGRP3
Entrez
Uniprot