RAPGEF3 Antibody

Western Blot: RAPGEF3 Antibody [H00010411-D01P] - Analysis of RAPGEF3 expression in mouse kidney.

Immunocytochemistry/Immunofluorescence: RAPGEF3 Antibody [H00010411-D01P] - Analysis of antibody to RAPGEF3 on HeLa cell. Antibody concentration 30 ug/ml.

Western Blot: RAPGEF3 Antibody [H00010411-D01P] - Analysis of RAPGEF3 expression in transfected 293T cell line by RAPGEF3 polyclonal antibody.Lane 1: RAPGEF3 transfected lysate(99.40 KDa).Lane 2: Non-transfected lysate.

Product Discontinued

RAPGEF3 Antibody Summary

• Immunogen: RAPGEF3 (NP_006096.2, 1 a.a. - 881 a.a.) full-length human protein. MVLRRMHRPRSCSYQLLLEHQRPSCIQGLRWTPLTNSEESLDFSESLEQASTERVLRAGRQLHRHLLATCPNLIRDRKYHLRLYRQCCSGRELVDGILALGLGVHSRSQVVGICQVLLDEGALCHVKHDWAFQDRDAQFYRFPGPEPEPVGTHEMEEELAEAVALLSQRGPDALLTVALRKPPGQRTDEELDLIFEELLHIKAVAHLSNSVKRELAAVLLFEPHSKAGTVLFSQGDKGTSWYIIWKGSVNVVTHGKGLVTTLHEGDDFGQLALVNDAPRAATIILREDNCHFLRVDKQDFNRIIKDVEAKTMRLEEHGKVVLVLERASQGAGPSRPPTPGRNRYTVMSGTPEKILELLLEAMGPDSSAHDPTETFLSDFLLTHRVFMPSAQLCAALLHHFHVEPAGGSEQERSTYVCNKRQQILRLVSQWVALYGSMLHTDPVATSFLQKLSDLVGRDTRLSNLLREQWPERRRCHRLENGCGNASPQMKARNLPVWLPNQDEPLPGSSCAIQVGDKVPYDICRPDHSVLTLQLPVTASVREVMAALAQEDGWTKGQVLVKVNSAGDAIGLQPDARGVATSLGLNERLFVVNPQEVHELIPHPDQLGPTVGSAEGLDLVSAKDLAGQLTDHDWSLFNSIHQVELIHYVLGPQHLRDVTTANLERFMRRFNELQYWVATELCLCPVPGPRAQLLRKFIKLAAHLKEQKNLNSFFAVMFGLSNSAISRLAHTWERLPHKVRKLYSALERLLDPSWNHRVYRLALAKLSPPVIPFMPLLLKDMTFIHEGNHTLVENLINFEKMRMMARAARMLHHCRSHNPVPLSPLRSRVSHLHEDSQVARISTCSEQSLSTRSPASTWAYVQQLKVIDNQRELSRLSRELEP
• Isotype: IgG
• Clonality: Polyclonal
• Host: Rabbit
• Gene: RAPGEF3
• Purity: Protein G purified

Applications/Dilutions

• Dilutions:
  • Immunocytochemistry/ Immunofluorescence
  • Western Blot
• Application Notes: This antibody is useful for Western Blot, Functional

Packaging, Storage & Formulations

• Storage: Aliquot and store at -20C or -80C. Avoid freeze-thaw cycles.
• Buffer: PBS (pH 7.4)
• Preservative: No Preservative
• Purity: Protein G purified

Notes

This product is produced by and distributed for Abnova, a company based in Taiwan.

Alternate Names for RAPGEF3 Antibody

• 9330170P05Rik
• bcm910
• cAMP-GEFI
• cAMP-regulated guanine nucleotide exchange factor I
• CGEF1
• EPAC 1
• EPAC
• EPAC1
• EPACRAP guanine-nucleotide-exchange factor (GEF) 3
• Exchange factor directly activated by cAMP 1
• Exchange protein directly activated by cAMP 1
• HSU79275
• MGC21410
• Rap guanine nucleotide exchange factor (GEF) 3
• rap guanine nucleotide exchange factor 3
• Rap1 guanine-nucleotide-exchange factor directly activated by cAMP
• RAPGEF3

Background

RAPGEF3, also known as Rap guanine nucleotide exchange factor 3, is a 104 kDa 923 amino acid protein with two shorter isoforms produced by alternative splicing. The gene is necessary for rearranging actin at cell to cell junctions. RAPGEF3 is currently being studied for its involvement with leukemia, melanoma, pancreatitis, thyroiditis, carcinoma, prostatitis and neuronitis. RAPGEF3 is linked to the chemotaxis, cell adhesion, insulin secretion, and immune system pathways where it interacts with GNAI2, GNAI1, PDE3B, RAP1A and RAP1B.

Limitations

This product is for research use only and is not approved for use in humans or in clinical diagnosis. Primary Antibodies are guaranteed for 1 year from date of receipt.

Bioinformatics

• Gene Symbol: RAPGEF3
• Uniprot:
  • NP_006096.2(Human)