RAPGEF3 Products

Description

RAPGEF3, also known as Rap guanine nucleotide exchange factor 3, is a 104 kDa 923 amino acid protein with two shorter isoforms produced by alternative splicing. The gene is necessary for rearranging actin at cell to cell junctions. RAPGEF3 is currently being studied for its involvement with leukemia, melanoma, pancreatitis, thyroiditis, carcinoma, prostatitis and neuronitis. RAPGEF3 is linked to the chemotaxis, cell adhesion, insulin secretion, and immune system pathways where it interacts with GNAI2, GNAI1, PDE3B, RAP1A and RAP1B.

Bioinformatics

Entrez	10411 Human
Uniprot	A8K2G5 Human AAH17728 Human NM_006105 Human NP_001092002 Human NP_006096.2 Human O95398 Human
Product By Gene ID	10411
Alternate Names	9330170P05Rik bcm910 CAMP-GEFI cAMP-GEFI cAMP-regulated guanine nucleotide exchange factor I CGEF1 EPAC 1 EPAC1 EPACRAP guanine-nucleotide-exchange factor (GEF) 3 Exchange factor directly activated by cAMP 1 Exchange protein directly activated by cAMP 1 HSU79275 MGC21410 Rap guanine nucleotide exchange factor (GEF) 3 rap guanine nucleotide exchange factor 3 Rap1 guanine-nucleotide-exchange factor directly activated by cAMP

Research Areas for RAPGEF3

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Signal Transduction