Rad51C Antibody (Rad51C 2H11/6) [DyLight 350]

• Reactivity: Hu
• Applications: WB, ICC/IF, IHC, IP
• Clone: Rad51C 2H11/6
• Clonality: Monoclonal
• Host: Mouse
• Conjugate: DyLight 350

Rad51C Antibody (Rad51C 2H11/6) [DyLight 350] Summary

• Description: This conjugate is made on demand and is not held in inventory. Each order represents a unique lot. All conjugates are generated using validated conjugation protocols and meet strict degree of labeling (F/P) specifications; additional information is available upon request. The antibody concentration is provided on the individual product label.
  
  For specialized conjugation needs, like large quantities, specific concentrations, and defined F/P ratios, bulk and custom antibody conjugation services are available.
• Immunogen: Rad51C 2H11/6 was raised against His-tagged human Rad51C, overexpressed in e.coli and purified on a talon affinity column under denaturing conditions, followed by gel purification on a SDS-Page
• Specificity: Rad51C 2H11/6 detects as little as 10ng of purified protein and also detects endogenouse hamster Rad51C in whole V79 cell extracts by western blotting.
• Isotype: IgG1
• Clonality: Monoclonal
• Host: Mouse
• Gene: RAD51C
• Purity: Protein A purified

Applications/Dilutions

• Dilutions:
  • Immunocytochemistry/ Immunofluorescence
  • Immunohistochemistry
  • Immunoprecipitation
  • Western Blot
• Application Notes: Recommended applications are based on validated applications from the unconjugated base product NBP2-50263. This conjugated antibody is not kept in inventory and is made to order using validated conjugation protocols.

Packaging, Storage & Formulations

• Storage: Store at 4C in the dark.
• Buffer: 50mM Sodium Borate
• Preservative: 0.05% Sodium Azide
• Purity: Protein A purified

Notes

DyLight (R) is a trademark of Thermo Fisher Scientific Inc. and its subsidiaries.

Alternate Names for Rad51C Antibody (Rad51C 2H11/6) [DyLight 350]

• BROVCA3
• DNA repair protein RAD51 homolog 3
• FANCO
• MGC104277
• R51H3
• RAD51 homolog C (S. cerevisiae)
• RAD51 homolog C
• RAD51L2RAD51 (S. cerevisiae) homolog C
• RAD51-like protein 2
• yeast RAD51 homolog 3

Background

The Rad51 DNA repair protein is a key component of the double-strand break repair pathway and is essential for mitotic and meiotic recombination and genomic stability. Five human Rad51 homologs have been identified: XRCC2, XRCC3, Rad51B, Rad51C, and Rad51D. Each of these homologs interacts with one or more of the others, with all of the proteins involved with either one complex or with multiple smaller complexes.

Limitations

This product is for research use only and is not approved for use in humans or in clinical diagnosis. Primary Antibodies are guaranteed for 1 year from date of receipt.

Bioinformatics

• Gene Symbol: RAD51C