Recombinant Human RAB23 Protein

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Product Details

Summary
Reactivity HuSpecies Glossary
Applications PAGE
Concentration
0.5 mg/ml

Order Details

Recombinant Human RAB23 Protein Summary

Description
A recombinant protein with a N-Terminal His-tag and corresponding to the amino acids 1-234 of Human RAB23

Source: E.coli

Amino Acid Sequence: MGSSHHHHHH SSGLVPRGSH MLEEDMEVAI KMVVVGNGAV GKSSMIQRYC KGIFTKDYKK TIGVDFLERQ IQVNDEDVRL MLWDTAGQEE FDAITKAYYR GAQACVLVFS TTDRESFEAV SSWREKVVAE VGDIPTVLVQ NKIDLLDDSC IKNEEAEALA KRLKLRFYRT SVKEDLNVNE VFKYLAEKYL QKLKQQIAED PELTHSSSNK IGVFNTSGGS HSGQNSGTLN GGDVINLRPN KQRTKKNRNP FSSC

Source
E. coli
Protein/Peptide Type
Recombinant Protein
Gene
RAB23
Purity
>90%, by SDS-PAGE

Applications/Dilutions

Theoretical MW
28.5 kDa.
Disclaimer note: The observed molecular weight of the protein may vary from the listed predicted molecular weight due to post translational modifications, post translation cleavages, relative charges, and other experimental factors.

Packaging, Storage & Formulations

Storage
Store at 4C short term. Aliquot and store at -20C long term. Avoid freeze-thaw cycles.
Buffer
20mM Tris-HCl buffer (pH8.0) containing 30% glycerol, 1mM DTT, 0.1mM PMSF
Preservative
No Preservative
Concentration
0.5 mg/ml
Purity
>90%, by SDS-PAGE

Alternate Names for Recombinant Human RAB23 Protein

  • DKFZp781H0695
  • HSPC137
  • MGC8900
  • RAB family small GTP binding protein RAB 23
  • RAB23, member RAS oncogene family
  • ras-related protein Rab-23

Background

RAB23, also known as ras-related protein Rab23, is a member of the Rab family of proteins and localizes to the cytoplasmic side of the cell membrane. This protein is thought to to play a role in intracellular protein transportation and signal transduction mediated by small GTPases. RAB23 is an essential negative regulator of the Sonic hedgehog signaling pathway. Mutations in the gene encoding RAB23 may result in Carpenter syndrome a condition characterized by obesity, cardiac defects, polysyndactyly and craniosynostosis. Recombinant human RAB23 protein, fused to His-tag at N-terminus, was expressed in E.coli and purified by using conventional chromatography.

Limitations

This product is for research use only and is not approved for use in humans or in clinical diagnosis. Peptides and proteins are guaranteed for 3 months from date of receipt.

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Bioinformatics

Gene Symbol RAB23