R-Spondin 1 Antibody (7A6)

Images

 
Western Blot: R-Spondin 1 Antibody (7A6) [NBP1-28867] - analysis using anti-R-spondin1 monoclonal antibody against recombinant R-spondin1 protein(1) and R-spondin1(aa21-263)-hIgGFc transfected HEK293 cell lysate(2).

Product Details

Summary
Reactivity HuSpecies Glossary
Applications WB, ELISA
Clone
7A6
Clonality
Monoclonal
Host
Mouse
Conjugate
Unconjugated

Order Details

R-Spondin 1 Antibody (7A6) Summary

Immunogen
Purified recombinant fragment of RSPO1 expressed in E. Coli.
Specificity
Specific for R-spondin1.
Isotype
IgG1
Clonality
Monoclonal
Host
Mouse
Gene
RSPO1
Purity
Unpurified
Innovator's Reward
Test in a species/application not listed above to receive a full credit towards a future purchase.

Applications/Dilutions

Dilutions
  • Western Blot 1:500-1:2000
  • ELISA 1:10000
Theoretical MW
28.9 kDa.
Disclaimer note: The observed molecular weight of the protein may vary from the listed predicted molecular weight due to post translational modifications, post translation cleavages, relative charges, and other experimental factors.

Reactivity Notes

Human.

Packaging, Storage & Formulations

Storage
Store at 4C short term. Aliquot and store at -20C long term. Avoid freeze-thaw cycles.
Buffer
Ascites
Preservative
0.03% Sodium Azide
Purity
Unpurified

Alternate Names for R-Spondin 1 Antibody (7A6)

  • Cristin 3
  • CRISTIN3
  • FLJ40906Roof plate-specific spondin-1
  • hRspo1
  • roof plate-specific spondin
  • RSPO
  • RSPO1
  • RSpondin 1
  • R-Spondin 1
  • R-spondin homolog (Xenopus laevis)
  • RSPONDIN
  • R-spondin1
  • R-spondin-1

Background

R-spondin1, also known as RSPO1, CRISTIN3, FLJ40906. Entrez Protein NP_001033722.1. It is a member of the R-spondin family and a 28.9kDa secreted activator protein with two cystein-rich, furin-like domains and one thrombospondin type 1 domain. In mice, the protein induces the rapid onset of crypt cell proliferation and increases intestinal epithelial healing, providing a protective effect against chemotherapy-induced adverse effects.It is activator of the beta-catenin signaling cascade, leading to TCF-dependent gene activation. Acts both in the canonical Wnt/beta-catenin-dependent pathway, possibly via a direct interaction with Wnt proteins, and in a Wnt-independent beta catenin pathway through a receptor signaling pathway that may not use frizzled/LRP receptors. Acts as a ligand for frizzled FZD8 and LRP6. May negatively regulate the TGF-beta pathway. Has a essential roles in ovary determination.

Limitations

This product is for research use only and is not approved for use in humans or in clinical diagnosis. Primary Antibodies are guaranteed for 1 year from date of receipt.

Customers Who Viewed This Item Also Viewed...

AF475
Species: Mu
Applications: WB, IHC
NBP2-37463
Species: Hu
Applications: WB, ELISA, Flow, IHC, CyTOF-ready
NBP1-54467
Species: Hu, Mu, Rt, Ch, Pm
Applications: WB, Simple Western, ICC/IF, IHC, IHC-P, IP
AF3075
Species: Hu
Applications: WB, ICC
NB100-1277
Species: Hu, Mu, Ft
Applications: WB, ChIP, ICC/IF, IHC, IHC-Fr, IHC-P, PEP-ELISA, IF, IHC-WhMt
PP-N1665-00
Species: Hu
Applications: WB, IHC, IP
PP-H7431-00
Species: Hu
Applications: WB
NBP1-28904
Species: Hu, Po
Applications: ICC/IF (-), WB, IHC, IHC-Fr, IHC-P
AF1505
Species: Hu
Applications: WB, Flow, CyTOF-ready
AF1647
Species: Mu
Applications: WB, Flow, IHC, CyTOF-ready
H00007536-M01
Species: Hu, Mu
Applications: WB, ELISA, ICC/IF, IHC-P, IP
NB110-60011
Species: Hu, Mu
Applications: WB, Simple Western, IHC, IHC-Fr, IHC-P, IP
NBP1-54467
Species: Hu, Mu, Rt, Ch, Pm
Applications: WB, Simple Western, ICC/IF, IHC, IHC-P, IP

Publications for R-Spondin 1 Antibody (NBP1-28867) (0)

There are no publications for R-Spondin 1 Antibody (NBP1-28867).
By submitting your publication information earn gift cards and discounts for future purchases.

Reviews for R-Spondin 1 Antibody (NBP1-28867) (0)

There are no reviews for R-Spondin 1 Antibody (NBP1-28867). By submitting a review you will receive an Amazon e-Gift Card or Novus Product Discount.
  • Review with no image -- $10/€7/£6/$10 CAD/¥70 Yuan/¥1110 Yen
  • Review with an image -- $25/€18/£15/$25 CAD/¥150 Yuan/¥2500 Yen
  • 1st to review with an image -- $50/€35/£30/$50 CAD/¥300 Yuan/¥5000 Yen

Product General Protocols

Find general support by application which include: protocols, troubleshooting, illustrated assays, videos and webinars.

Video Protocols

WB Video Protocol

FAQs for R-Spondin 1 Antibody (NBP1-28867) (0)

There are no specific FAQs related to this product. Read our general customer & technical service FAQs.

Secondary Antibodies

 

Isotype Controls

Additional R-Spondin 1 Products

Bioinformatics Tool for R-Spondin 1 Antibody (NBP1-28867)

Discover related pathways, diseases and genes to R-Spondin 1 Antibody (NBP1-28867). Need help? Read the Bioinformatics Tool Guide for instructions on using this tool.
Visit Tool

Diseases for R-Spondin 1 Antibody (NBP1-28867)

Discover more about diseases related to R-Spondin 1 Antibody (NBP1-28867).
 

Pathways for R-Spondin 1 Antibody (NBP1-28867)

View related products by pathway.

PTMs for R-Spondin 1 Antibody (NBP1-28867)

Learn more about PTMs related to R-Spondin 1 Antibody (NBP1-28867).

Blogs on R-Spondin 1

There are no specific blogs for R-Spondin 1, but you can read our latest blog posts.

Customers Who Bought This Also Bought

Contact Information

Product PDFs

Calculators

Concentration Calculator

The concentration calculator allows you to quickly calculate the volume, mass or concentration of your vial. Simply enter your mass, volume, or concentration values for your reagent and the calculator will determine the rest.

=
÷

Review this Product

Be the first to review our R-Spondin 1 Antibody (7A6) and receive a gift card or discount.

Bioinformatics

Gene Symbol RSPO1
Entrez