PYHIN1 Antibody

Images

 
Orthogonal Strategies: Immunohistochemistry-Paraffin: PYHIN1 Antibody [NBP2-13835] - Staining in human tonsil and liver tissues using NBP2-13835 antibody. Corresponding PYHIN1 RNA-seq data are presented for the ...read more
Immunohistochemistry-Paraffin: PYHIN1 Antibody [NBP2-13835] - Staining of human liver shows no positivity in hepatocytes as expected.
Immunohistochemistry-Paraffin: PYHIN1 Antibody [NBP2-13835] - Staining of human rectum shows moderate cytoplasmic/ nuclear positivity in lymphoid cells.
Immunohistochemistry-Paraffin: PYHIN1 Antibody [NBP2-13835] - Staining of human testis shows weak nuclear positivity in a small subset of cells in seminiferous ducts.
Immunohistochemistry-Paraffin: PYHIN1 Antibody [NBP2-13835] - Staining of human tonsil shows moderate nuclear positivity in non-germinal center cells.

Product Details

Summary
Reactivity HuSpecies Glossary
Applications IHC
Clonality
Polyclonal
Host
Rabbit
Conjugate
Unconjugated
Validated by:
       

Orthogonal Strategies

 

Order Details

PYHIN1 Antibody Summary

Immunogen
This antibody was developed against a recombinant protein corresponding to the amino acids: IESIPVKGIIPSKKTKQKEVYPATPACTPSNRLTAKGAEETLGPQKRKKPSEEETGTKRSKMSKEQTRPSCS
Isotype
IgG
Clonality
Polyclonal
Host
Rabbit
Gene
PYHIN1
Purity
Immunogen affinity purified
Innovator's Reward
Test in a species/application not listed above to receive a full credit towards a future purchase.

Applications/Dilutions

Dilutions
  • Immunohistochemistry 1:200 - 1:500
  • Immunohistochemistry-Paraffin 1:200 - 1:500
Application Notes
For IHC-Paraffin, HIER pH 6 retrieval is recommended.
Control Peptide
PYHIN1 Protein (NBP2-13835PEP)

Packaging, Storage & Formulations

Storage
Store at 4C short term. Aliquot and store at -20C long term. Avoid freeze-thaw cycles.
Buffer
PBS (pH 7.2) and 40% Glycerol
Preservative
0.02% Sodium Azide
Purity
Immunogen affinity purified

Alternate Names for PYHIN1 Antibody

  • IFIXMGC23885
  • Interferon-inducible protein X
  • pyrin and HIN domain family, member 1
  • pyrin and HIN domain-containing protein 1
  • RP11-520H16.1

Background

PYHIN1 belongs to the HIN200 family of interferon-inducible proteins that share a 200-amino acid signature motif attheir C-terminal ends. HIN200 proteins are primarily nuclear and are involved in transcriptional regulation of genesimportant for cell cycle control, differentiation, and apoptosis (Ding et al., 2006 (PubMed 16479015)).(supplied byOMIM)

Limitations

This product is for research use only and is not approved for use in humans or in clinical diagnosis. Primary Antibodies are guaranteed for 1 year from date of receipt.

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Bioinformatics

Gene Symbol PYHIN1