Western Blot: IFI202b Antibody [NBP2-27066] - Analysis of Ifi202b in mouse spleen tissue lysate in the 1) absence and 2) presence of immunizing peptide, and 3) NIH 3T3 cell lysate using this antibody. Goat anti-rabbit ...read more
Mouse. Human reactivity reported in scientific literature (PMID: 24131791).
Packaging, Storage & Formulations
Storage
Store at 4C short term. Aliquot and store at -20C long term. Avoid freeze-thaw cycles.
Buffer
0.2 ml PBS and 0.05% BSA
Preservative
0.05% Sodium Azide
Concentration
0.5 mg/ml
Purity
Protein A purified
Notes
This product shares 91% sequence homology with Human IFI16
Background
Interferon-activable protein 202 (Ifi202b, p202) belongs to the HIN-200 family and contains two HIN-200 domains. It is reported to inhibit transcriptional activity of several transcription factors, including NF-kappaB p50 and p65, FOS, JUN, E2F1, E2F4, MYOD1 and myogenin. It has anti-apoptotic effects due to inhibition of the transcriptional activity of p53. It is an interferon-inducible protein which is responsible for Lupus susceptibility and is induced by Interleukin-6.
Limitations
This product is for research use only and is not approved for use in humans or in clinical diagnosis. Primary Antibodies are guaranteed for 1 year from date of receipt.
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