PTP beta/zeta/PTPRZ Antibody (279244) [DyLight 405]

• Reactivity: Hu
• Applications: WB
• Clone: 279244
• Clonality: Monoclonal
• Host: Rat
• Conjugate: DyLight 405

PTP beta/zeta/PTPRZ Antibody (279244) [DyLight 405] Summary

• Immunogen: E. coli-derived recombinant human PTP beta / zeta /PTPRZ
  Gly302-Asn754
  Accession # P23471
• Specificity: Detects human PTP beta / zeta /PTPRZ in Western blots.
• Isotype: IgG1
• Clonality: Monoclonal
• Host: Rat
• Gene: PTPRZ1
• Purity: Protein A or G purified from hybridoma culture supernatant

Applications/Dilutions

• Dilutions:
  • Western Blot
• Application Notes: Optimal dilution of this antibody should be experimentally determined.

Packaging, Storage & Formulations

• Storage: Store at 4C in the dark.
• Buffer: 50mM Sodium Borate
• Preservative: 0.05% Sodium Azide
• Purity: Protein A or G purified from hybridoma culture supernatant

Notes

DyLight (R) is a trademark of Thermo Fisher Scientific Inc. and its subsidiaries.

Alternate Names for PTP beta/zeta/PTPRZ Antibody (279244) [DyLight 405]

• 3F8 CSPG
• HPTPZ
• phosphacan
• protein tyrosine phosphatase, receptor-type, Z polypeptide 1
• PTP beta/zeta
• PTP18
• PTPRZ
• PTPRZ1
• PTPZ
• receptor-type, zeta polypeptide 1
• RPTPB
• RPTPbeta

Background

PTPRB is a member of the protein tyrosine phosphatase (PTP) family. The family comprises at least 37 proteins, characterized by a catalytic phosphatase domain of approximately 240 amino acids, and includes both transmembrane and cytosolic enzymes. PTP1B is a transmembrane PTP. The PTPs have high substrate specificity for phosphotyrosyl proteins, at the primary sequence level sharing little similarity with the protein serine phosphatases, protein threonine phosphatases, or the acid and alkaline phosphatases. PTP beta interacts with and regulates the tyrosine phosphorylation level of catenins, which are critical in physiological and pathological events such as cell migration, adhesion and transformation.

Limitations

This product is for research use only and is not approved for use in humans or in clinical diagnosis. Primary Antibodies are guaranteed for 1 year from date of receipt.

Bioinformatics

• Gene Symbol: PTPRZ1