PTHLH/PTHrP Antibody


Western Blot: PTHLH Antibody [NBP1-74098] - Mouse Brain Lysate 1ug/ml Gel Concentration 10-20%
Immunohistochemistry-Paraffin: PTHLH Antibody [NBP1-74098] - Human Lung tissue, 5ug/ml.

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PTHLH/PTHrP Antibody Summary

Synthetic peptides corresponding to the middle region of Pthlh. Immunizing peptide sequence EVSPNSKPAPNTKNHPVRFGSDDEGRYLTQETNKVETYKEQPLKTPGKKK.
Immunogen affinity purified
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  • Western Blot 1 ug/ml
  • Immunohistochemistry 1:10-1:500
  • Immunohistochemistry-Paraffin 1:10-1:500
Application Notes
This is a rabbit polyclonal antibody against Pthlh and was validated on Western blot.
Theoretical MW
16 kDa.
Disclaimer note: The observed molecular weight of the protein may vary from the listed predicted molecular weight due to post translational modifications, post translation cleavages, relative charges, and other experimental factors.

Packaging, Storage & Formulations

Store at -20C. Avoid freeze-thaw cycles.
PBS & 2% Sucrose.
No Preservative
Immunogen affinity purified


The addition of 50% glycerol is optional for those storing this antibody at -20C and not aliquoting smaller units. However, please note that glycerol may interrupt some downstream antibody applications and should be added with caution.

Alternate Names for PTHLH/PTHrP Antibody

  • BDE2
  • HHM
  • MGC14611
  • Osteostatin
  • parathyroid hormone-like hormone
  • Parathyroid hormone-like protein
  • parathyroid hormone-related protein
  • PLPosteostatin
  • PTHR
  • PTH-related protein
  • PTH-rP
  • PTHRPparathyroid hormone-like related protein


Pthlh is a neuroendocrine peptide which is a critical regulator of cellular and organ growth, development, migration, differentiation and survival and of epithelial calcium ion transport. It regulates endochondral bone development and epithelial-mesenchymal interactions during the formation of the mammary glands and teeth. It is required for skeletal homeostasis. It promotes mammary mesenchyme differentiation and bud outgrowth by modulating mesenchymal cell responsiveness to BMPs. It upregulates BMPR1A expression in the mammary mesenchyme and this increases the sensitivity of these cells to BMPs and allows them to respond to BMP4 in a paracrine and/or autocrine fashion. BMP4 signaling in the mesenchyme, in turn, triggers epithelial outgrowth and augments MSX2 expression, which causes the mammary mesenchyme to inhibit hair follicle formation within the nipple sheath.


This product is for research use only and is not approved for use in humans or in clinical diagnosis. Primary Antibodies are guaranteed for 1 year from date of receipt.

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Gene Symbol PTHLH