Recombinant Human PTH 15N Stable Isotope Protein

SDS-Page: Human PTH 15N 7 - 84 a.a Protein [NBP2-35217]

• Reactivity: Hu
• Applications: PAGE
• Format: Carrier-Free
• Concentration: LYOPH

Recombinant Human PTH 15N Stable Isotope Protein Summary

• Description: A single non-glycosylated polypeptide chain containing 78 amino acids corresponding to 15N stable isotope labeled PTH Source: E. coli

  Uniprot ID: P01270

  Amino Acid Sequence: LMHNLGKHLN SMERVEWLRK KLQDVHNFVA LGAPLAPRDA GSQRPRKKED NVLVESHEKS LGEADKADVN VLTKAKSQ

• Details of Functionality: Test in Process.
• Source: E. coli
• Protein/Peptide Type: Recombinant Protein
• Gene: PTH
• Purity: > 98 % pure by SDS-PAGE and HPLC
• Endotoxin Note: Less than 0.1 EU/ug of PTH as determined by LAL method.

Applications/Dilutions

• Dilutions:
  • SDS-Page
• Theoretical MW: 8.9 kDa.
  Disclaimer note: The observed molecular weight of the protein may vary from the listed predicted molecular weight due to post translational modifications, post translation cleavages, relative charges, and other experimental factors.

Packaging, Storage & Formulations

• Storage: Store at -20 to -70C as supplied. After reconstitution, store at 2 to 8C for 1 month and at -20 to -70C for long term storage. Avoid repeated freeze-thaw cycles.
• Buffer: Lyophilized from a 0.2 um filtered concentrated solution in PBS, pH 7.4.
• Preservative: No Preservative
• Concentration: LYOPH
• Purity: > 98 % pure by SDS-PAGE and HPLC
• Reconstitution Instructions: Recommended to centrifuge prior to opening. Reconstitute in sterile distilled water or aqueous buffer containing 0.1% BSA to a concentration of 0.1-1.0mg/mL.

Alternate Names for Recombinant Human PTH 15N Stable Isotope Protein

• Parathormone
• Parathyrin
• parathyroid hormone 1
• parathyroid hormone
• PTH
• PTH1

Background

Parathyroid hormone (PTH) is a single polypeptide of 78 amino acids. It is a critical hormone in the regulation of Ca2+ homeostasis and secreted by the parathyroid glands, which promote release of calcium from bone to extracellular fluid by activating osteoblasts and inhibiting osteoclasts, indirectly promote increased intestinal absorption of calcium, and promote renal tubular reabsorption of calcium and increased renal excretion of phosphates. It is a major regulator of bone metabolism. Secretion of parathyroid hormone increases when the level of calcium in the extracellular fluid is low.

Limitations

This product is for research use only and is not approved for use in humans or in clinical diagnosis. Peptides and proteins are guaranteed for 3 months from date of receipt.

Bioinformatics

• Gene Symbol: PTH
• Uniprot:
  • P01270()
  • P01270()
  • P01270()