PTH Antibody (3H9 + PTH/1175) [Alexa Fluor® 405]

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Product Details

Summary
Reactivity HuSpecies Glossary
Applications Flow, IHC, IHC-P
Clone
3H9 + PTH/1175
Clonality
Monoclonal
Host
Mouse
Conjugate
Alexa Fluor 405

Order Details

PTH Antibody (3H9 + PTH/1175) [Alexa Fluor® 405] Summary

Immunogen
Synthetic peptide corresponding to amino acids 1 to 34 of PTH conjugated to a carrier (3H9); Recombinant fragment (84 amino acid residues from C-terminus) of human PTH protein
Localization
Cytoplasmic and Secreted
Specificity
Epitope of this MAb maps in the C-terminus of PTH, a hormone produced by the parathyroid gland that regulates the concentration of calcium and phosphorus in extracellular fluid. This hormone elevates blood Ca2+ levels by dissolving the salts in bone and preventing their renal excretion.It is produced in the parathyroid gland as an 84 amino acid single chain polypeptide. It can also be secreted as N-terminal truncated fragments or C-terminal fragments after intracellular degradation, as in case of hypercalcemia. Defects in this gene are a cause of familial isolated hypoparathyroidism (FIH); also called autosomal dominant hypoparathyroidism or autosomal dominant hypocalcemia. FIH is characterized by hypocalcemia and hyperphosphatemia due to inadequate secretion of parathyroid hormone. Symptoms are seizures, tetany and cramps. FIH exist both as autosomal dominant and recessive forms of hypoparathyroidism.
Isotype
IgG2b
Clonality
Monoclonal
Host
Mouse
Gene
PTH
Purity
Protein A or G purified
Innovator's Reward
Test in a species/application not listed above to receive a full credit towards a future purchase.

Applications/Dilutions

Dilutions
  • Flow Cytometry
  • Immunohistochemistry
  • Immunohistochemistry-Paraffin
Application Notes
Optimal dilution of this antibody should be experimentally determined.

Packaging, Storage & Formulations

Storage
Store at 4C in the dark.
Buffer
50mM Sodium Borate
Preservative
0.05% Sodium Azide
Purity
Protein A or G purified

Notes

Alexa Fluor (R) products are provided under an intellectual property license from Life Technologies Corporation. The purchase of this product conveys to the buyer the non-transferable right to use the purchased product and components of the product only in research conducted by the buyer (whether the buyer is an academic or for-profit entity). The sale of this product is expressly conditioned on the buyer not using the product or its components, or any materials made using the product or its components, in any activity to generate revenue, which may include, but is not limited to use of the product or its components: (i) in manufacturing; (ii) to provide a service, information, or data in return for payment; (iii) for therapeutic, diagnostic or prophylactic purposes; or (iv) for resale, regardless of whether they are resold for use in research. For information on purchasing a license to this product for purposes other than as described above, contact Life Technologies Corporation, 5791 Van Allen Way, Carlsbad, CA 92008 USA or outlicensing@lifetech.com. This conjugate is made on demand. Actual recovery may vary from the stated volume of this product. The volume will be greater than or equal to the unit size stated on the datasheet.

Alternate Names for PTH Antibody (3H9 + PTH/1175) [Alexa Fluor® 405]

  • Parathormone
  • Parathyrin
  • parathyroid hormone 1
  • parathyroid hormone
  • PTH
  • PTH1

Limitations

This product is for research use only and is not approved for use in humans or in clinical diagnosis. Primary Antibodies are guaranteed for 1 year from date of receipt.

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Secondary Antibodies

 

Isotype Controls

Other Available Formats

Alexa Fluor 350 NBP2-47731AF350
Alexa Fluor 405 NBP2-47731AF405
Alexa Fluor 405 NBP2-45116AF405
Alexa Fluor 488 NBP2-47731AF488
Alexa Fluor 488 NBP2-45116AF488
Alexa Fluor 532 NBP2-47731AF532
Alexa Fluor 594 NBP2-47731AF594
Alexa Fluor 647 NBP2-47731AF647
Alexa Fluor 647 NBP2-45116AF647
Alexa Fluor 700 NBP2-47731AF700
Alexa Fluor 700 NBP2-45116AF700
Alexa Fluor 750 NBP2-47731AF750
Allophycocyanin NBP2-47731APC
Allophycocyanin NBP2-45116APC
Allophycocyanin/Cy7 NBP2-47731APCCY7
Biotin NBP2-47731B
Biotin NBP2-45116B
DyLight 350 NBP2-45116UV
DyLight 350 NBP2-47731UV
DyLight 405 NBP2-47731V
DyLight 405 NBP2-45116V
DyLight 488 NBP2-45116G
DyLight 488 NBP2-47731G
DyLight 550 NBP2-45116R
DyLight 550 NBP2-47731R
DyLight 594 NBP2-47731DL594
DyLight 650 NBP2-47731C
DyLight 650 NBP2-45116C
DyLight 680 NBP2-47731FR
DyLight 680 NBP2-45116FR
DyLight 755 NBP2-47731IR
DyLight 755 NBP2-45116IR
FITC NBP2-47731F
FITC NBP2-45116F
HRP NBP2-47731H
HRP NBP2-45116H
Janelia Fluor 549 NBP2-47731JF549
Janelia Fluor 646 NBP2-47731JF646
PE NBP2-47731PE
PE NBP2-45116PE
PE/Atto594 NBP2-47731PEATT594
PE/Cy5.5 NBP2-47731PECY55
PE/Cy7 NBP2-47731PECY7
PerCP NBP2-45116PCP
PerCP NBP2-47731PCP

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