PSD-95 Antibody (EP2652Y)

Product Discontinued

PSD-95 Antibody (EP2652Y) Summary

• Immunogen: A synthetic peptide corresponding to residues in the N-terminus of human PSD95 was used as an immunogen.
• Marker: post-Synaptic Marker
• Isotype: IgG
• Clonality: Monoclonal
• Host: Rabbit
• Gene: DLG4
• Purity: Tissue culture supernatant

Applications/Dilutions

• Dilutions:
  • Flow Cytometry 1:20
  • Immunocytochemistry/ Immunofluorescence 1:100-250
  • Immunoprecipitation 1:10
  • Western Blot 1:1000-5000
• Application Notes: This product is useful for: Western Blot, Immunocytochemistry, Immunoprecipitation, Flow Cytometry. In Western blot this antibody detects a band at approximately 95kDa.
• Theoretical MW: 95 kDa.
  Disclaimer note: The observed molecular weight of the protein may vary from the listed predicted molecular weight due to post translational modifications, post translation cleavages, relative charges, and other experimental factors.

Packaging, Storage & Formulations

• Storage: Store at -20C. Avoid freeze-thaw cycles.
• Buffer: 49% PBS, 0.05% BSA and 50% Glycerol
• Preservative: 0.01% Sodium Azide
• Purity: Tissue culture supernatant

Notes

Produced using Abcam's RabMab® technology. RabMab® technology is covered by the following U.S. Patents, No. 5,675,063 and/or 7,429,487.

Alternate Names for PSD-95 Antibody (EP2652Y)

• discs, large homolog 4 (Drosophila)
• disks large homolog 4
• DLG4
• FLJ97752
• FLJ98574
• Postsynaptic density protein 95
• post-synaptic density protein 95
• PSD95
• PSD-95
• PSD95SAP90SAP-90discs large homolog 4
• SAP90
• Synapse-associated protein 90
• Tax interaction protein 15

Background

This gene encodes a member of the membrane-associated guanylate kinase (MAGUK) family. It heteromultimerizes with another MAGUK protein, DLG2, and is recruited into NMDA receptor and potassium channel clusters. These two MAGUK proteins may interact at postsynaptic sites to form a multimeric scaffold for the clustering of receptors, ion channels, and associated signaling proteins. Multiple transcript variants encoding different isoforms have been found for this gene.

Limitations

This product is for research use only and is not approved for use in humans or in clinical diagnosis. Primary Antibodies are guaranteed for 1 year from date of receipt.

Bioinformatics

• Gene Symbol: DLG4
• Entrez:
  • 1742(Human)
• Uniprot:
  • P78352(Human)