PRPF31 Antibody

Product Discontinued

PRPF31 Antibody Summary

• Immunogen: PRPF31 (NP_056444, 400 a.a. ~ 500 a.a) partial recombinant protein with GST tag.GKSGSGRVRQTQVNEATKARISKTLQRTLQKQSVVYGGKSTIRDRSSGTASSVAFTPLQGLEIVNPQAAEKKVAEANQKYFSSMAEFLKVKGEKSGLMST
• Specificity: PRPF31 - PRP31 pre-mRNA processing factor 31 homolog (yeast)
• Isotype: IgG
• Clonality: Polyclonal
• Host: Mouse
• Gene: PRPF31
• Purity: Unpurified

Applications/Dilutions

• Dilutions:
  • ELISA
  • Western Blot 1:500
• Application Notes: Antibody reactive against cell lysate and recombinant protein for western blot. It has also been used for ELISA.

Reactivity Notes

Human. Other species not tested.

Packaging, Storage & Formulations

• Storage: Aliquot and store at -20C or -80C. Avoid freeze-thaw cycles.
• Buffer: 50% Glycerol
• Preservative: No Preservative
• Purity: Unpurified

Notes

This product is produced by and distributed for Abnova, a company based in Taiwan.

Alternate Names for PRPF31 Antibody

• DKFZp566J153
• hPrp31
• NY-BR-99
• Pre-mRNA-processing factor 31
• Protein 61K
• PRP31 pre-mRNA processing factor 31 homolog (S. cerevisiae)
• PRP31 pre-mRNA processing factor 31 homolog (yeast)
• PRP31RP11
• Serologically defined breast cancer antigen NY-BR-99
• U4/U6 small nuclear ribonucleoprotein Prp31
• U4/U6 snRNP 61 kDa protein

Background

PRPF31 is a component of the spliceosome complex. It is recruited to introns following the attachment of U4 and U6 (MIM 180692) RNAs and the 15.5K protein (NHP2L1; MIM 601304). The addition of PRPF31 is crucial for the transition of the spliceosomal complex to the activated state (Liu et al., 2007) [PubMed 17412961].[supplied by OMIM]

Limitations

This product is for research use only and is not approved for use in humans or in clinical diagnosis. Primary Antibodies are guaranteed for 1 year from date of receipt.

Publications for PRPF31 Antibody (H00026121-A01)(1)

Publication using H00026121-A01

• Nag A, Steitz JA. Tri-snRNP-associated proteins interact with subunits of the TRAMP and nuclear exosome complexes, linking RNA decay and pre-mRNA splicing. RNA Biol. 2012-03-01 [PMID: 22336707] (Human)

Bioinformatics

• Gene Symbol: PRPF31
• Entrez:
  • 26121(Human)
• OMIM:
  • 600138(Human)
• Uniprot:
  • NP_056444(Human)