Proteinase 3/Myeloblastin/PRTN3 Antibody

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Order Details


    • Catalog Number
      NBP1-90262
    • Availability
      Product Discontinued

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Proteinase 3/Myeloblastin/PRTN3 Antibody Summary

Immunogen
This antibody was developed against Recombinant Protein corresponding to amino acids: PTQQHFSVAQVFLNNYDAENKLNDILLIQLSSPANLSASVATVQLPQQDQPVPHGTQCLAMGWGRVGAHDPPAQVLQELNVTVVTFFCRPHNICTFVPRRKAGICFGDSGGPLICDGI
Isotype
IgG
Clonality
Polyclonal
Host
Rabbit
Gene
PRTN3
Purity
Immunogen affinity purified
Innovator's Reward
Test in a species/application not listed above to receive a full credit towards a future purchase.

Applications/Dilutions

Dilutions
  • Immunohistochemistry 1:200 - 1:500
  • Immunohistochemistry-Paraffin 1:200 - 1:500
Application Notes
For IHC-Paraffin, HIER pH 6 retrieval is recommended.

Packaging, Storage & Formulations

Storage
Store at 4C short term. Aliquot and store at -20C long term. Avoid freeze-thaw cycles.
Buffer
PBS (pH 7.2) and 40% Glycerol
Preservative
0.02% Sodium Azide
Purity
Immunogen affinity purified

Alternate Names for Proteinase 3/Myeloblastin/PRTN3 Antibody

  • ACPA
  • AGP7
  • AGP7PR3
  • azurophil granule protein 7
  • C-ANCA
  • EC 3.4.21
  • EC 3.4.21.76
  • Leukocyte proteinase 3
  • MBN
  • MBT
  • Myeloblastin
  • Neutrophil proteinase 4
  • NP4
  • NP-4
  • P29C-ANCA antigen
  • PR-3CANCA
  • Proteinase 3
  • PRTN3
  • serine proteinase, neutrophil
  • Wegener autoantigen
  • Wegener granulomatosis autoantigen

Background

Myeloblastin (PR3) is a polymorphonuclear leukocyte serine protease which degrades elastin, fibronectin, laminin, vitronectin, and collagen types I, III, and IV (in vitro) and causes emphysema when administered by tracheal insufflation to hamsters. PR3 plays a role in neutrophil response to inflammation.

Limitations

This product is for research use only and is not approved for use in humans or in clinical diagnosis. Primary Antibodies are guaranteed for 1 year from date of receipt.

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Product General Protocols

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FAQs for Proteinase 3/Myeloblastin/PRTN3 Antibody (NBP1-90262). (Showing 1 - 1 of 1 FAQ).

  1. What is the best tissue to be used as a positive control for this antibody?
    • For IHC we recommend using bone marrow as a positive control. For Western blot, we used an overexpression lysate.

Secondary Antibodies

 

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Bioinformatics

Gene Symbol PRTN3