Proteinase 3/Myeloblastin/PRTN3 Antibody (3B4)

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Western Blot: Proteinase 3/Myeloblastin/PRTN3 Antibody (3B4) [NBP1-51573] - Western blot analysis using PRTN3 mouse mAb against PRTN3 (aa28-256)-hIgGFc transfected HEK293 cell lysate (1).

Product Details

Summary
Reactivity HuSpecies Glossary
Applications WB, ELISA
Clone
3B4
Clonality
Monoclonal
Host
Mouse
Conjugate
Unconjugated
Concentration
1.0 mg/ml

Proteinase 3/Myeloblastin/PRTN3 Antibody (3B4) Summary

Immunogen
Purified recombinant fragment of human Proteinase 3 expressed in E. Coli.
Isotype
IgG2b
Clonality
Monoclonal
Host
Mouse
Gene
PRTN3
Purity
Protein G purified
Innovator's Reward
Test in a species/application not listed above to receive a full credit towards a future purchase.

Applications/Dilutions

Dilutions
  • Western Blot 1:500-1:2000
  • ELISA 1:10000
Theoretical MW
28 kDa.
Disclaimer note: The observed molecular weight of the protein may vary from the listed predicted molecular weight due to post translational modifications, post translation cleavages, relative charges, and other experimental factors.

Packaging, Storage & Formulations

Storage
Store at 4C short term. Aliquot and store at -20C long term. Avoid freeze-thaw cycles.
Buffer
PBS and 50% Glycerol
Preservative
0.03% Sodium Azide
Concentration
1.0 mg/ml
Purity
Protein G purified

Alternate Names for Proteinase 3/Myeloblastin/PRTN3 Antibody (3B4)

  • ACPA
  • AGP7
  • AGP7PR3
  • azurophil granule protein 7
  • C-ANCA
  • EC 3.4.21
  • EC 3.4.21.76
  • Leukocyte proteinase 3
  • MBN
  • MBT
  • Myeloblastin
  • Neutrophil proteinase 4
  • NP4
  • NP-4
  • P29C-ANCA antigen
  • PR-3CANCA
  • Proteinase 3
  • PRTN3
  • serine proteinase, neutrophil
  • Wegener autoantigen
  • Wegener granulomatosis autoantigen

Background

Myeloblastin (PR3) is a polymorphonuclear leukocyte serine protease which degrades elastin, fibronectin, laminin, vitronectin, and collagen types I, III, and IV (in vitro) and causes emphysema when administered by tracheal insufflation to hamsters. PR3 plays a role in neutrophil response to inflammation.

Limitations

This product is for research use only and is not approved for use in humans or in clinical diagnosis. Primary Antibodies are guaranteed for 1 year from date of receipt.

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Publications for Proteinase 3/Myeloblastin/PRTN3 Antibody (NBP1-51573) (0)

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Bioinformatics Tool for Proteinase 3/Myeloblastin/PRTN3 Antibody (NBP1-51573)

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Bioinformatics

Gene Symbol PRTN3
Entrez