Recombinant Human Procalcitonin Protein

SDS-Page: Recombinant Human Procalcitonin Protein [NBP1-99303]

Product Discontinued

Recombinant Human Procalcitonin Protein Summary

• Description: Recombinant bioactive protein containing 116 amino acids for Human Procalcitonin
  
  Source:E. coli
  Amino Acid Sequence:(P01258)
  
  This product is manufactured by Abcam and distributed by Novus Biologicals. (Abcam Catalog Number: ab285450)
• Preparation Method: Determined to be >97% pure by SDS-PAGE
• Details of Functionality: Human Procalcitonin was tested using Biomerieux reagents on the Min-Vidas. The assay was run at 80 ng/ml with a recovery of 82 percent.
• Source: E. coli
• Protein/Peptide Type: Recombinant Protein
• Gene: CALCA
• Purity: >97%, by SDS-PAGE

Applications/Dilutions

• Dilutions:
  • Bioactivity
  • SDS-Page
• Theoretical MW: 13.2 kDa.
  Disclaimer note: The observed molecular weight of the protein may vary from the listed predicted molecular weight due to post translational modifications, post translation cleavages, relative charges, and other experimental factors.

Packaging, Storage & Formulations

• Storage: Store at -20 to -80C. Avoid freeze-thaw cycles.
• Buffer: Lyophilized from 10 mM sodium phosphate (pH 7.5)
• Concentration: Lyoph
• Purity: >97%, by SDS-PAGE
• Reconstitution Instructions: Centrifuge the vial prior to opening. Reconstitute in sterile H2O to a concentration of 0.1 mg/ml.

Alternate Names for Recombinant Human Procalcitonin Protein

• CALC1
• CALCA
• Calcitonin 1
• calcitonin gene-related peptide 1
• CGRP
• Katacalcin
• Procalcitonin

Background

Procalcitonin is a peptide hormone mainly produced by the C cells of the thyroid and certain endocrine cells of the lung. Under normal expression conditions, procalcitonin is immediately cleaved into three specific fragments, an N terminal residue, calcitonin and katacalcin. Levels of unprocessed Procalcitonin rise significantly after bacterial infection, trauma or shock. Recombinant Human Procalcitonin produced in E.coli is a single, non-glycosylated, polypeptide chain containing 116 amino acids with a molecular weight of 12,796 Daltons.

Limitations

This product is for research use only and is not approved for use in humans or in clinical diagnosis. Peptides and proteins are guaranteed for 3 months from date of receipt.

Bioinformatics

• Gene Symbol: CALCA