Recombinant Human PRL-2/PTP4A2 Protein

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SDS-Page: Recombinant Human PRL-2/PTP4A2 Protein [NBP1-48362] - 15 % SDS-PAGE (3ug)

Product Details

Summary
Reactivity HuSpecies Glossary
Applications PAGE
Concentration
0.5 mg/ml

Order Details

Recombinant Human PRL-2/PTP4A2 Protein Summary

Description
A recombinant protein with a N-Terminal His-tag and corresponding to the amino acids 1-167 of Human PRL-2/PTP4A2

Source: E.coli

Amino Acid Sequence: MRGSHHHHHH GMASMTGGQQ MGRDLYDDDD KDRWGSMNRP APVEISYENM RFLITHNPTN ATLNKFTEEL KKYGVTTLVR VCDATYDKAP VEKEGIHVLD WPFDDGAPPP NQIVDDWLNL LKTKFREEPG CCVAVHCVAG LGRAPVLVAL ALIECGMKYE DAVQFIRQKR RGAFNSKQLL YLEKYRPKMR LRFRDTNGHC CVQ

Source
E. coli
Protein/Peptide Type
Recombinant Protein
Gene
PTP4A2
Purity
>90%, by SDS-PAGE

Applications/Dilutions

Theoretical MW
23.2 kDa.
Disclaimer note: The observed molecular weight of the protein may vary from the listed predicted molecular weight due to post translational modifications, post translation cleavages, relative charges, and other experimental factors.

Packaging, Storage & Formulations

Storage
Store at 4C short term. Aliquot and store at -20C long term. Avoid freeze-thaw cycles.
Buffer
20mM Tris-HCl buffer (pH 8.0) containing 1mM DTT, 10% glycerol
Preservative
No Preservative
Concentration
0.5 mg/ml
Purity
>90%, by SDS-PAGE

Alternate Names for Recombinant Human PRL-2/PTP4A2 Protein

  • EC 3.1.3.48
  • HH13
  • HH7-2
  • HU-PP-1
  • HU-PP-1HH13
  • OV-1
  • OV-1PTP4A
  • PRL2
  • PRL-2
  • PRL-2HH7-2
  • PRL2protein tyrosine phosphatase IVA
  • protein tyrosine phosphatase IVA2
  • protein tyrosine phosphatase type IVA 2
  • protein tyrosine phosphatase type IVA, member 2
  • Protein-tyrosine phosphatase 4a2
  • Protein-tyrosine phosphatase of regenerating liver 2
  • PTP(CAAXII)
  • PTP4A2
  • PTPCAAX2
  • PTPCAAX2phosphatase of regenerating liver 2
  • ptp-IV1a
  • ptp-IV1b

Background

Protein tyrosine phosphatase type IVA 2 isoform 1, also known as PTP4A2, belongs to a small class of the protein tyrosine phosphatase (PTP) family. PTP4A2 is localized to the early endosome that play regulatory roles in a variety of cellular processes. This protein was found to interact with the beta-subunit of Rab geranylgeranyltransferase II (beta GGT II), and thus may function as a regulator of GGT II activity. Overexpression of this gene in mammalian cells conferred a transformed phenotype, which suggested its role in tumorigenesis. Recombinant human PTP4A2 protein, fused to His-tag at N-terminus, was expressed in E.coli and purified by using conventional chromatography techniques.

Limitations

This product is for research use only and is not approved for use in humans or in clinical diagnosis. Peptides and proteins are guaranteed for 3 months from date of receipt.

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Bioinformatics

Gene Symbol PTP4A2
Entrez