PRL-2/PTP4A2 Antibody (RB18592)

Product Discontinued

PRL-2/PTP4A2 Antibody (RB18592) Summary

• Immunogen: This PTP4A2 antibody is generated from rabbits immunized with a KLH conjugated synthetic peptide between 32-59 amino acids from the Central region of human PTP4A2.
• Localization: Cellular Location Cell membrane. Early endosome. Cytoplasm. Tissue Location Ubiquitously expressed, with highest levels in skeletal muscle, heart and thymus. Overexpressed in prostate tumor tissue
• Isotype: IgG
• Clonality: Polyclonal
• Host: Rabbit
• Gene: PTP4A2
• Purity: Protein A purified

Applications/Dilutions

• Dilutions:
  • Flow Cytometry 1:10 - 1:50
  • Immunocytochemistry/ Immunofluorescence 1:10 - 1:50
  • Immunohistochemistry
  • Immunohistochemistry-Paraffin 1:50 - 1:100
  • Western Blot 1:1000
• Theoretical MW: 19.127 kDa.
  Disclaimer note: The observed molecular weight of the protein may vary from the listed predicted molecular weight due to post translational modifications, post translation cleavages, relative charges, and other experimental factors.

Reactivity Notes

Predicted to react with Mouse and Rat.

Packaging, Storage & Formulations

• Storage: Store at 4C short term. Aliquot and store at -20C long term. Avoid freeze-thaw cycles.
• Buffer: PBS
• Preservative: 0.09% Sodium Azide
• Concentration: 1.29 mg/ml
• Purity: Protein A purified

Alternate Names for PRL-2/PTP4A2 Antibody (RB18592)

• EC 3.1.3.48
• HH13
• HH7-2
• HU-PP-1
• HU-PP-1HH13
• OV-1
• OV-1PTP4A
• PRL2
• PRL-2
• PRL-2HH7-2
• PRL2protein tyrosine phosphatase IVA
• protein tyrosine phosphatase IVA2
• protein tyrosine phosphatase type IVA 2
• protein tyrosine phosphatase type IVA, member 2
• Protein-tyrosine phosphatase 4a2
• Protein-tyrosine phosphatase of regenerating liver 2
• PTP(CAAXII)
• PTP4A2
• PTPCAAX2
• PTPCAAX2phosphatase of regenerating liver 2
• ptp-IV1a
• ptp-IV1b

Background

PTP4A2 belongs to a small class of the protein tyrosine phosphatase (PTP) family. PTPs are cell signaling molecules that play regulatory roles in a variety of cellular processes. PTPs in this class contain a protein tyrosine phosphatase catalytic domain and a characteristic C-terminal prenylation motif. This PTP has been shown to primarily associate with plasmic and endosomal membrane through its C-terminal prenylation. This PTP was found to interact with the beta-subunit of Rab geranylgeranyltransferase II (beta GGT II), and thus may function as a regulator of GGT II activity.

Limitations

This product is for research use only and is not approved for use in humans or in clinical diagnosis. Primary Antibodies are guaranteed for 1 year from date of receipt.

Bioinformatics

• Gene Symbol: PTP4A2
• Uniprot:
  • Q12974(Human)