PRL-2/PTP4A2 Antibody (015) [Alexa Fluor® 700]

• Reactivity: Hu
• Applications: ELISA
• Clone: 015
• Clonality: Monoclonal
• Host: Rabbit
• Conjugate: Alexa Fluor 700

PRL-2/PTP4A2 Antibody (015) [Alexa Fluor® 700] Summary

• Additional Information: Recombinant Monoclonal Antibody
• Immunogen: This antibody was obtained from a rabbit immunized with purified, recombinant Human PRL-2/PTP4A2 (Uniprot#: Q12974-1; Asn2-Gln167).
• Source: HEK293
• Isotype: IgG
• Clonality: Monoclonal
• Host: Rabbit
• Gene: PTP4A2
• Purity: Protein A purified

Applications/Dilutions

• Dilutions:
  • ELISA
• Application Notes: Optimal dilution of this antibody should be experimentally determined.

Packaging, Storage & Formulations

• Storage: Store at 4C in the dark.
• Buffer: 50mM Sodium Borate
• Preservative: 0.05% Sodium Azide
• Purity: Protein A purified

Notes

Alexa Fluor (R) products are provided under an intellectual property license from Life Technologies Corporation. The purchase of this product conveys to the buyer the non-transferable right to use the purchased product and components of the product only in research conducted by the buyer (whether the buyer is an academic or for-profit entity). The sale of this product is expressly conditioned on the buyer not using the product or its components, or any materials made using the product or its components, in any activity to generate revenue, which may include, but is not limited to use of the product or its components: (i) in manufacturing; (ii) to provide a service, information, or data in return for payment; (iii) for therapeutic, diagnostic or prophylactic purposes; or (iv) for resale, regardless of whether they are resold for use in research. For information on purchasing a license to this product for purposes other than as described above, contact Life Technologies Corporation, 5791 Van Allen Way, Carlsbad, CA 92008 USA or outlicensing@lifetech.com. This conjugate is made on demand. Actual recovery may vary from the stated volume of this product. The volume will be greater than or equal to the unit size stated on the datasheet.

Alternate Names for PRL-2/PTP4A2 Antibody (015) [Alexa Fluor® 700]

• EC 3.1.3.48
• HH13
• HH7-2
• HU-PP-1
• HU-PP-1HH13
• OV-1
• OV-1PTP4A
• PRL2
• PRL-2
• PRL-2HH7-2
• PRL2protein tyrosine phosphatase IVA
• protein tyrosine phosphatase IVA2
• protein tyrosine phosphatase type IVA 2
• protein tyrosine phosphatase type IVA, member 2
• Protein-tyrosine phosphatase 4a2
• Protein-tyrosine phosphatase of regenerating liver 2
• PTP(CAAXII)
• PTP4A2
• PTPCAAX2
• PTPCAAX2phosphatase of regenerating liver 2
• ptp-IV1a
• ptp-IV1b

Background

PTP4A2 is encoded by this gene belongs to a small class of the protein tyrosine phosphatase (PTP) family. PTPs are cell signaling molecules that play regulatory roles in a variety of cellular processes. PTPs in this class contain a protein tyrosine phosphatase catalytic domain and a characteristic C-terminal prenylation motif. This PTP has been shown to primarily associate with plasmic and endosomal membrane through its C-terminal prenylation. This PTP was found to interact with the beta-subunit of Rab geranylgeranyltransferase II (beta GGT II), and thus may function as a regulator of GGT II activity. Overexpression of this gene in mammalian cells conferred a transformed phenotype, which suggested its role in tumorigenesis. Alternatively spliced transcript variants that encode two distinct isoforms have been described. [provided by RefSeq]

Limitations

This product is for research use only and is not approved for use in humans or in clinical diagnosis. Primary Antibodies are guaranteed for 1 year from date of receipt.

Bioinformatics

• Gene Symbol: PTP4A2