Recombinant Human PRDC/GREM2 Protein

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Product Details

Summary
Reactivity HuSpecies Glossary
Applications PAGE
Concentration
Lyoph

Order Details

Recombinant Human PRDC/GREM2 Protein Summary

Description
Recombinant bioactive protein for Human PRDC/GREM2

Source:E. coli
Amino Acid Sequence:(Q9H772)

Source
E. coli
Protein/Peptide Type
Recombinant Protein
Gene
GREM2
Purity
>95%, by SDS-PAGE
Endotoxin Note
<0.1 ng/ug

Applications/Dilutions

Theoretical MW
17.2 kDa.
Disclaimer note: The observed molecular weight of the protein may vary from the listed predicted molecular weight due to post translational modifications, post translation cleavages, relative charges, and other experimental factors.

Packaging, Storage & Formulations

Storage
Store at -20 to -80C. Avoid freeze-thaw cycles.
Buffer
Sterile filtered and lyophilized with no additives
Concentration
Lyoph
Purity
>95%, by SDS-PAGE
Reconstitution Instructions
Reconstitute to 1 mg/ml with sterilized dH2O. Pipette to dissolve the protein pellet completely

Alternate Names for Recombinant Human PRDC/GREM2 Protein

  • CKTSF1B2
  • CKTSF1B2FLJ21195
  • Cysteine knot superfamily 1, BMP antagonist 2
  • DAN domain family member 3
  • DAND3
  • DAND3Prdc
  • GREM2
  • gremlin 2
  • gremlin 2, cysteine knot superfamily, homolog
  • gremlin-2
  • PRDC
  • PRDCgremlin 2, cysteine knot superfamily, homolog (Xenopus laevis)
  • Protein related to DAN and cerberus

Background

Gremlin (also known as Increased in High Glucose Protein 2, IHG-2, Down-regulated in Mos-transformed cells protein, Drm) functions as a bone morphogenetic protein (BMP) antagonist. It acts by binding to, and forming heterodimers with BMP-2, BMP-4, BMP-7, thus preventing them from interacting with their cell surface receptors. Recombinant human Gremlin-2 is a N-terminus His-tagged protein that was expressed from E. coli.

Limitations

This product is for research use only and is not approved for use in humans or in clinical diagnosis. Peptides and proteins are guaranteed for 3 months from date of receipt.

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Bioinformatics

Gene Symbol GREM2
Entrez