PRDC/GREM2 Antibody Pair

Product Discontinued

PRDC/GREM2 Antibody Pair Summary

• Description: Quality control test: Immunoprecipitation-Western Blot (IP-WB). This IP-WB antibody pair set comes with one antibody for immunoprecipitation and another to detect the precipitated protein in western blot.
  
  
• Antibody pair for IP: rabbit polyclonal anti-GREM2 (300 ul)
• Antibody pair for WB: mouse purified polyclonal anti-GREM2 (50 ug)
• Clonality: Polyclonal
• Gene: GREM2
• Purity: Immunogen affinity purified

Applications/Dilutions

• Dilutions:
  • Immunoprecipitation
  • Western Blot

Packaging, Storage & Formulations

• Storage: Aliquot and store at -20C or -80C. Avoid freeze-thaw cycles.
• Buffer: 1x PBS, pH 7.4
• Preservative: No Preservative
• Purity: Immunogen affinity purified

Notes

This product is produced by and distributed for Abnova, a company based in Taiwan.

Alternate Names for PRDC/GREM2 Antibody Pair

• CKTSF1B2
• CKTSF1B2FLJ21195
• Cysteine knot superfamily 1, BMP antagonist 2
• DAN domain family member 3
• DAND3
• DAND3Prdc
• GREM2
• gremlin 2
• gremlin 2, cysteine knot superfamily, homolog
• gremlin-2
• PRDC
• PRDCgremlin 2, cysteine knot superfamily, homolog (Xenopus laevis)
• Protein related to DAN and cerberus

Background

GREM2, also known as Gremlin-2, is a 168 amino acid that is 19 kDa, belongs to the DAN family, plays a role in the inhibition of the activity of BMP2 and BMP4 in a dose-dependent manner, and as an antagonist of BMP, it may play a role in regulating organogenesis, body patterning, and tissue differentiation. Current research is being performed on several diseases and disorders including astigmatism, myopia, accommodative esotropia, keratoconus, intraocular retinoblastoma, scimitar syndrome, swine influenza, influenza, norrie disease, and multiple sclerosis. The GREM2 protein is known to have an interaction with BMP4, BMP2, CER1, NOG, and FSTL1 in signal transduction and signaling by BMP pathways.

Limitations

This product is for research use only and is not approved for use in humans or in clinical diagnosis. Antibody Pairs are guaranteed for 6 months from date of receipt.

Bioinformatics

• Gene Symbol: GREM2