PPP1R9B/Spinophilin Antibody

Product Discontinued

PPP1R9B/Spinophilin Antibody Summary

• Immunogen: A synthetic peptide from aa region 450-500 of human Spinophilin conjugated to blue carrier protein was used as the antigen. The peptide is homologous in mouse and rat.
• Clonality: Polyclonal
• Host: Rabbit
• Gene: PPP1R9B
• Purity: Unpurified

Applications/Dilutions

• Dilutions:
  • Immunohistochemistry 1:1000 - 1:2000
  • Immunohistochemistry-Paraffin 1:1000 - 1:2000
  • Western Blot 1:1000 - 1:2000

Packaging, Storage & Formulations

• Storage: Store at 4C short term. Aliquot and store at -20C long term. Avoid freeze-thaw cycles.
• Buffer: Lyophilized from whole serum
• Preservative: No Preservative
• Purity: Unpurified

Alternate Names for PPP1R9B/Spinophilin Antibody

• FLJ30345
• neurabin II
• Neurabin-2
• neurabin-II
• PPP1R6
• PPP1R9
• PPP1R9B
• Protein phosphatase 1 regulatory subunit 9B
• protein phosphatase 1, regulatory (inhibitor) subunit 9B
• protein phosphatase 1, regulatory subunit 9B, spinophilin
• SPINO
• Spinophilin
• Spn

Background

Spinophilin, also known as Neurabin-2 and PPP1R9B, has 815 amino acids and is approximately 89kDa. Spinophilin is a scaffold protein that is involved in many signaling pathways, such as the cAMP pathway, the G-protein coupled receptor signaling pathway, the IL-6 pathway, and the Beta-Adrenergic signaling pathway. Spinophilin may be implicated in the linking of the plasma membrane to the actin cytoskeleton at synaptic junctions. Current research on Spinophilin is being performed in relation to several diseases and disorders including anorexia nervosa, Alzheimer's disease, schizophrenia, encephalitis, breast cancer, mood disorder, and glioblastoma. Spinophilin has also been shown to have interactions with CCKAR, CCKBR, ADRA1B, DRD2, and PPP1CA.

Limitations

This product is for research use only and is not approved for use in humans or in clinical diagnosis. Primary Antibodies are guaranteed for 1 year from date of receipt.

Bioinformatics

• Gene Symbol: PPP1R9B