PPIH Antibody

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Western Blot: PPIH Antibody [NB100-75346] - E coli-derived fusion protein as test antigen. Affinity-purified IgY dilution: 1:2000, Goat anti-IgY-HRP dilution: 1:1000. Colorimetric method for signal development. ( ...read more

Product Details

Summary
Reactivity Hu, MuSpecies Glossary
Applications WB
Clonality
Polyclonal
Host
Chicken
Conjugate
Unconjugated

Order Details

PPIH Antibody Summary

Immunogen
The immunogen for this antibody was a sequence from 1a.a. to 177a.a. from PPIH(a 177a.a. long protein)
Localization
Nucleus; nucleolus. Nucleus; nucleoplasm; Cajal body. Also localized to Cajal bodies (coiled bodies). Mitochondrion; mitochondrial matrix.
Specificity
PPIH
Clonality
Polyclonal
Host
Chicken
Gene
PPIH
Purity
Immunogen affinity purified
Innovator's Reward
Test in a species/application not listed above to receive a full credit towards a future purchase.

Applications/Dilutions

Dilutions
  • Western Blot 1:100-1:2000
Application Notes
Western Blot: E coli-derived fusion protein as test antigen. Affinity-purified IgY dilution: 1:2000. Goat anti-IgY-HRP dilution: 1:1000. Colorimetric method for signal development.
Positive Control
PPIH Lysate (NBL1-14650)

Reactivity Notes

This antibody is reactive against Human, mouse.

Packaging, Storage & Formulations

Storage
Store at 4C short term. Aliquot and store at -20C long term. Avoid freeze-thaw cycles.
Buffer
PBS
Preservative
No Preservative
Purity
Immunogen affinity purified

Alternate Names for PPIH Antibody

  • cyclophilin H
  • CYP20
  • CypH
  • CYPHpeptidyl prolyl isomerase H (cyclophilin H)
  • EC 5.2.1.8
  • MGC5016
  • peptidyl-prolyl cis-trans isomerase H
  • peptidylprolyl isomerase H (cyclophilin H)
  • PPIase H
  • Rotamase H
  • Small nuclear ribonucleoprotein particle-specific cyclophilin H
  • SnuCyp-20
  • USA-CyP SnuCyp-20
  • USA-CYPCYP-20
  • U-snRNP-associated cyclophilin SnuCyp-20
  • U-snRNP-associated cyclophilin SunCyp-20

Background

PPIases accelerate the folding of proteins. It catalyzes the cis trans isomerization of proline imidic peptide bonds in oligopeptides. Participates in pre mRNA splicing. May play a role in the assembly of the U4/U5/U6 tri snRNP complex. May act as a chaperone. The protein encoded by this gene is a member of the peptidyl prolyl cis trans isomerase (PPIase) family. PPIases catalyze the cis trans isomerization of proline imidic peptide bonds in oligopeptides and accelerate the folding of proteins. This protein is a specific component of the complex that includes pre mRNA processing factors PRPF3, PRPF4, and PRPF18, as well as U4/U5/U6 tri snRNP. This protein has been shown to possess PPIase activity and may act as a protein chaperone that mediates the interactions between different proteins inside the spliceosome.

Limitations

This product is for research use only and is not approved for use in humans or in clinical diagnosis. Primary Antibodies are guaranteed for 1 year from date of receipt.

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Product General Protocols

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Video Protocols

WB Video Protocol

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Positive Control Lysate(s)

Secondary Antibodies

 

Isotype Controls

Additional PPIH Products

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Diseases for PPIH Antibody (NB100-75346)

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Bioinformatics

Gene Symbol PPIH
Entrez
Uniprot