PPIH Antibody (OTI1C6)

Western Blot: PPIH Antibody (1C6) [NBP2-45381] - Analysis of HEK293T cells were transfected with the pCMV6-ENTRY control (Left lane) or pCMV6-ENTRY PPIH.

Western Blot: PPIH Antibody (1C6) [NBP2-45381] - Analysis of A549 cell lysate (35ug).

• Reactivity: Hu, Mu, Rt
• Applications: WB
• Clone: OTI1C6
• Clonality: Monoclonal
• Host: Mouse
• Conjugate: Unconjugated
• Concentration: 1 mg/ml

PPIH Antibody (OTI1C6) Summary

• Description: Novus Biologicals Mouse PPIH Antibody (OTI1C6) (NBP2-45381) is a monoclonal antibody validated for use in WB. All Novus Biologicals antibodies are covered by our 100% guarantee.
• Immunogen: Full length human recombinant protein of human PPIH (NP_006338) produced in E.coli.
• Isotype: IgG1
• Clonality: Monoclonal
• Host: Mouse
• Gene: PPIH
• Purity: Immunogen affinity purified

Applications/Dilutions

• Dilutions:
  • Western Blot 1:2000
• Theoretical MW: 19 kDa.
  Disclaimer note: The observed molecular weight of the protein may vary from the listed predicted molecular weight due to post translational modifications, post translation cleavages, relative charges, and other experimental factors.

Packaging, Storage & Formulations

• Storage: Store at -20C. Avoid freeze-thaw cycles.
• Buffer: PBS (pH 7.3), 1.0% BSA and 50% Glycerol
• Preservative: 0.02% Sodium Azide
• Concentration: 1 mg/ml
• Purity: Immunogen affinity purified

Alternate Names for PPIH Antibody (OTI1C6)

• cyclophilin H
• CYP20
• CypH
• CYPHpeptidyl prolyl isomerase H (cyclophilin H)
• EC 5.2.1.8
• MGC5016
• peptidyl-prolyl cis-trans isomerase H
• peptidylprolyl isomerase H (cyclophilin H)
• PPIase H
• Rotamase H
• Small nuclear ribonucleoprotein particle-specific cyclophilin H
• SnuCyp-20
• USA-CyP SnuCyp-20
• USA-CYPCYP-20
• U-snRNP-associated cyclophilin SnuCyp-20
• U-snRNP-associated cyclophilin SunCyp-20

Background

PPIases accelerate the folding of proteins. It catalyzes the cis trans isomerization of proline imidic peptide bonds in oligopeptides. Participates in pre mRNA splicing. May play a role in the assembly of the U4/U5/U6 tri snRNP complex. May act as a chaperone. The protein encoded by this gene is a member of the peptidyl prolyl cis trans isomerase (PPIase) family. PPIases catalyze the cis trans isomerization of proline imidic peptide bonds in oligopeptides and accelerate the folding of proteins. This protein is a specific component of the complex that includes pre mRNA processing factors PRPF3, PRPF4, and PRPF18, as well as U4/U5/U6 tri snRNP. This protein has been shown to possess PPIase activity and may act as a protein chaperone that mediates the interactions between different proteins inside the spliceosome.

Limitations

This product is for research use only and is not approved for use in humans or in clinical diagnosis. Primary Antibodies are guaranteed for 1 year from date of receipt.

Bioinformatics

• Gene Symbol: PPIH