PNR/NR2E3 Antibody

Western Blot: PNR/NR2E3 Antibody [H00010002-B01P] - Analysis of NR2E3 expression in transfected 293T cell line by NR2E3 polyclonal antibody. Lane 1: NR2E3 transfected lysate(45.1 KDa). Lane 2: Non-transfected lysate.

Product Discontinued

PNR/NR2E3 Antibody Summary

• Immunogen: NR2E3 (NP_055064.1, 1 a.a. - 410 a.a.) full-length human protein. METRPTALMSSTVAAAAPAAGAASRKESPGRWGLGEDPTGVSPSLQCRVCGDSSSGKHYGIYACNGCSGFFKRSVRRRLIYRCQVGAGMCPVDKAHRNQCQACRLKKCLQAGMNQDAVQNERQPRSTAQVHLDSMESNTESRPESLVAPPAPAGRSPRGPTPMSAARALGHHFMASLITAETCAKLEPEDADENIDVTSNDPEFPSSPYSSSSPCGLDSIHETSARLLFMAVKWAKNLPVFSSLPFRDQVILLEEAWSELFLLGAIQWSLPLDSCPLLAPPEASAAGGAQGRLTLASMETRVLQETISRFRALAVDPTEFACMKALVLFKPETRGLKDPEHVEALQDQSQVMLSQHSKAHHPSQPVRFGKLLLLLPSLRFITAERIELLFFRKTIGNTPMEKLLCDMFKN
• Isotype: IgG
• Clonality: Polyclonal
• Host: Mouse
• Gene: NR2E3
• Purity: Protein G purified

Applications/Dilutions

• Dilutions:
  • Western Blot
• Application Notes: This antibody is useful for Western Blot, Functional

Packaging, Storage & Formulations

• Storage: Aliquot and store at -20C or -80C. Avoid freeze-thaw cycles.
• Buffer: PBS (pH 7.4)
• Preservative: No Preservative
• Purity: Protein G purified

Notes

This product is produced by and distributed for Abnova, a company based in Taiwan.

Alternate Names for PNR/NR2E3 Antibody

• NR2E3
• Nuclear receptor subfamily 2 group E member 3
• nuclear receptor subfamily 2, group E, member 3
• photoreceptor-specific nuclear receptor
• PNR
• PNRESCS
• rd7
• Retina-specific nuclear receptor
• RNR
• RP37MGC49976

Background

Photoreceptor-specific nuclear receptor (PNR), a NR2 Hepatocyte NF4-Like Receptor, has been suggested to affect cone cell proliferation in eye development. It has been shown to have a role in determining photoreceptor phenotype during human retinogenesis. In RD7 mice, a deletion in PNR results in hereditary retinal dysplasia and degeneration. A homozygous missense mutation in PNR has been linked to retinitis pigmentosa in Crypto-Jews of Belmonte. Two alternatively spliced isoforms have been documented. PNR is expressed in the retina. ESTs have been isolated from cancerous human lung, colon, and ovary, and from normal human eye.

Limitations

This product is for research use only and is not approved for use in humans or in clinical diagnosis. Primary Antibodies are guaranteed for 1 year from date of receipt.

Bioinformatics

• Gene Symbol: NR2E3
• Uniprot:
  • NP_055064.1(Human)