PNMA1 Antibody

Western Blot: PNMA1 Antibody [H00009240-D01P] - Analysis of PNMA1 expression in mouse testis.

Western Blot: PNMA1 Antibody [H00009240-D01P] - Analysis of PNMA1 expression in IMR-32.

Western Blot: PNMA1 Antibody [H00009240-D01P] - Analysis of PNMA1 expression in human stomach.

Western Blot: PNMA1 Antibody [H00009240-D01P] - Analysis of PNMA1 expression in transfected 293T cell line by PNMA1 polyclonal antibody.Lane 1: PNMA1 transfected lysate(39.80 KDa).Lane 2: Non-transfected lysate.

Product Discontinued

PNMA1 Antibody Summary

• Immunogen: PNMA1 (NP_006020.4, 1 a.a. - 353 a.a.) full-length human protein. MAMTLLEDWCRGMDVNSQRALLVWGIPVNCDEAEIEETLQAAMPQVSYRMLGRMFWREENAKAALLELTGAVDYAAIPREMPGKGGVWKVLFKPPTSDAEFLERLHLFLAREGWTVQDVARVLGFQNPTPTPGPEMPAEMLNYILDNVIQPLVESIWYKRLTLFSGRDIPGPGEETFDPWLEHTNEVLEEWQVSDVEKRRRLMESLRGPAADVIRILKSNNPAITTAECLKALEQVFGSVESSRDAQIKFLNTYQNPGEKLSAYVIRLEPLLQKVVEKGAIDKDNVNQARLEQVIAGANHSGAIRRQLWLTGAGEGPAPNLFQLLVQIREEEAKEEEEEAEATLLQLGLEGHF
• Specificity: PNMA1 - paraneoplastic antigen MA1,
• Isotype: IgG
• Clonality: Polyclonal
• Host: Rabbit
• Gene: PNMA1
• Purity: Protein A purified

Applications/Dilutions

• Dilutions:
  • Western Blot 1:500
• Application Notes: Antibody reactive against Recombinant Protein with GST tag on ELISA and Western Blot and also on transfected lysate in western blot. GST tag alone is used as a negative control.

Packaging, Storage & Formulations

• Storage: Aliquot and store at -20C or -80C. Avoid freeze-thaw cycles.
• Buffer: PBS (pH 7.4)
• Preservative: No Preservative
• Purity: Protein A purified

Notes

This product is produced by and distributed for Abnova, a company based in Taiwan.

Alternate Names for PNMA1 Antibody

• MA1Neuron- and testis-specific protein 1,37 kDa neuronal protein
• paraneoplastic antigen MA1
• paraneoplastic neuronal antigen MA1

Background

PNMA1 (Paraneoplastic antigen MA1) is a protein that is highly restricted to the brain and testis. A paraneoplastic phenomenon is a disease or symptom that is the consequence of the presence of cancer in the body, but is not due to the local presence of cancer cells. These phenomena are mediated by humoral factors (by hormones or cytokines) excreted by tumor cells or by an immune response against the tumor. Sometimes the symptoms of paraneoplastic syndromes show even before the diagnosis of a malignancy. Paraneoplastic syndromes can be divided into 4 main categories: mucocutane paraneoplastic syndromes, neurological paraneoplastic syndromes, haematological paraneoplastic syndromes and endocrine metabolic syndromes. Antibodies against PNMA1 are present in sera from patients suffering from paraneoplastic neurological disorders.

Limitations

This product is for research use only and is not approved for use in humans or in clinical diagnosis. Primary Antibodies are guaranteed for 1 year from date of receipt.

Publications for PNMA1 Antibody (H00009240-D01P)(1)

Publication using H00009240-D01P

• Auger C, Moudgalya H, Neely MR et al. Development of a Novel Circulating Autoantibody Biomarker Panel for the Identification of Patients with 'Actionable' Pulmonary Nodules Cancers (Basel) 2023-04-12 [PMID: 37190187] (Human)

Bioinformatics

• Gene Symbol: PNMA1
• Entrez:
  • 9240(Human)
• Uniprot:
  • NP_006020.4(Human)