PMS2 Antibody (BLR142H)

Western Blot;PMS2 Antibody (BLR142H) Whole cell lysate (25 µg) from U2OS, Hep-G2, K-562, LNCaP, GaMG, HeLa, Jurkat, and A-549 cells prepared using NETN lysis buffer. Antibody: Rabbit anti-PMS2 recombinant monoclonal antibody used at 1:1000. Secondary: HRP-conjugated goat anti-rabbit IgG . Detection: Chemiluminescence with an exposure time of 30 seconds. Lower Panel: Rabbit anti-COPB2 antibody.

• Reactivity: Hu
• Applications: WB, Flow, IP
• Clone: BLR142H
• Clonality: Monoclonal
• Host: Rabbit
• Conjugate: Unconjugated

PMS2 Antibody (BLR142H) Summary

• Description: Novus Biologicals Rabbit PMS2 Antibody (BLR142H) (NBP3-14722) is a recombinant monoclonal antibody validated for use in WB, Flow and IP. All Novus Biologicals antibodies are covered by our 100% guarantee.
• Additional Information: Recombinant Monoclonal
• Immunogen: between 550 and 600
• Clonality: Monoclonal
• Host: Rabbit
• Gene: PMS2
• Purity: >95%

Applications/Dilutions

• Dilutions:
  • Flow Cytometry
  • Immunoprecipitation
  • Western Blot

Packaging, Storage & Formulations

• Storage: Store at 2 - 8 C / 1 year from date of receipt
• Buffer: Borate Buffered Saline (BBS) pH 8.2 with 0.1% BSA and
• Preservative: 0.09% Sodium Azide
• Purity: >95%

Alternate Names for PMS2 Antibody (BLR142H)

• DNA mismatch repair protein PMS2
• EC 3.1
• H_DJ0042M02.9
• HNPCC4postmeiotic segregation increased (S. cerevisiae) 2
• mismatch repair endonuclease PMS2
• PMS1 protein homolog 2
• PMS2 postmeiotic segregation increased 2 (S. cerevisiae)
• PMSL2PMS2CL

Background

PMS2 is one of the PMS2 gene family members found in clusters on chromosome 7. The product of this gene is involved in DNA mismatch repair. It forms a heterodimer with MLH1 and this complex interacts with other complexes bound to mismatched bases. Mutations in this gene are associated with hereditary nonpolyposis colorectal cancer, Turcot syndrome, and are a cause of supratentorial primitive neuroectodermal tumors. Alternatively spliced transcript variants have been observed for this gene.

Limitations

This product is for research use only and is not approved for use in humans or in clinical diagnosis. Primary Antibodies are guaranteed for 1 year from date of receipt.

Bioinformatics

• Gene Symbol: PMS2